Evidence map›Paper›PMID 33262663›Full record

ReviewJournal of experimental pharmacology2020

Antiviral Effects of Oleandrin.

Robert A Newman, K Jagannadha Sastry, Ravit Arav-Boger, Hongyi Cai, Rick Matos, Robert Harrod

Open access · goldAbstract readReview
In one paragraph

Review in Journal of experimental pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Stress-induced translocation of the endoplasmic reticulum chaperone GRP78/BiP and its impact on human disease and therapy.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Antiviral activity of oleandrin and a defined extract of Nerium oleander against SARS-CoV-2.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Article
  12. Antiviral effects of oleandrin.Journal of the American College of Emergency Physicians open · 2021
    Article
  13. Article
  14. Toxicity of herbal medications suggested as treatment for COVID-19: A narrative review.Journal of the American College of Emergency Physicians open · 2021
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Robert A NewmanDepartment of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77054, USA.
K Jagannadha SastryDepartments of Thoracic, Head and Neck Medical Oncology and Veterinary Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Ravit Arav-BogerDivision of Infectious Diseases, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Hongyi CaiNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-8021-8493
Rick MatosInnovar, LLC, Plano, TX 75025, USA.ORCID 0000-0002-2124-523X
Robert HarrodDepartment of Biological Sciences, the Dedman College Center for Drug Discovery, Design & Delivery, Southern Methodist University, Dallas, TX 75275, USA.ORCID 0000-0003-0808-0343
The University of Texas MD Anderson Cancer Center · USMedical College of Wisconsin · USNational Institutes of Health · USSouthern Methodist University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past 15 years, investigators have reported on the utility and safety of cardiac glycosides for numerous health benefits including those as treatments for malignant disease, stroke-mediated ischemic injury and certain neurodegenerative diseases. In addition to those, there is a growing body of evidence for novel antiviral effects of selected cardiac glycoside molecules. One unique cardiac glycoside, oleandrin derived from

Indexed as

antiviral therapyK-ATPaseNaNerium oleanderoleandrinvirus

Identifiers

PMID33262663
PMCPMC7686471
OpenAlexW3105748304

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.