Evidence map›Paper›PMID 33262627›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2020

The Beneficial Role of

Toyin Dorcas Alabi, Charon de Villiers, Stephan S du Plessis, Thomas K Monsees, Nicole L Brooks, Oluwafemi Omoniyi Oguntibeju

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Leaf Extracts ofPlants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Toyin Dorcas AlabiPhytomedicine & Phytochemistry Group, Oxidative Stress Research Centre, Department of Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, South Africa.ORCID 0000-0001-9036-5545
Charon de VilliersPUDAC-Delft Animal Facility, South African Medical Research Council, Cape Town 7505, South Africa.ORCID 0000-0002-5000-7521
Stephan S du PlessisDivision of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg 7505, South Africa.ORCID 0000-0003-4617-4367
Thomas K MonseesDepartment of Medical Biosciences, University of the Western Cape, Bellville 7535, South Africa.
Nicole L BrooksFaculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Cape Town, South Africa.
Oluwafemi Omoniyi OguntibejuPhytomedicine & Phytochemistry Group, Oxidative Stress Research Centre, Department of Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, South Africa.ORCID 0000-0002-7299-1128
Cape Peninsula University of Technology · ZASouth African Medical Research Council · ZAStellenbosch University · ZAUniversity of the Western Cape · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProgression of diabetes mellitus has increasingly led to several diabetic complications. Diabetes is one of the major factors implicated in male reproductive system damage. Recent approaches such as the use of medicinal plants have been explored in the management of diabetes and associated complications.

methodsType 2 diabetes was induced in male Wistar rats with 10% fructose administration for 2 weeks and an intraperitoneal injection of 40mg/kgBW of streptozotocin. Aqueous extract (200mg and 400mg/kgBW) of

resultsDiabetes induction resulted in significant decrease in sperm concentration, viability and some motility parameters with 40% abnormalities in sperm morphology. The administration of

conclusionThe potency

Indexed as

Anchomanes difformisdiabetes mellitusmale fertilitysperm function

Identifiers

PMID33262627
PMCPMC7698316
OpenAlexW3108876520

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.