Evidence map›Paper›PMID 33262586›Full record

ArticleInternational journal of nanomedicine2020

Calcium-siRNA Nanocomplexes Optimized by Bovine Serum Albumin Coating Can Achieve Convenient and Efficient siRNA Delivery for Periodontitis Therapy.

Yang Wang, Wen Song, Yi Cui, Yang Zhang, Shenglin Mei, Qintao Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yang WangState Key Laboratory of Military Stomatology, Department of Periodontology, School of Stomatology, Air Force Medical University, Xi'an, People's Republic of China.
Wen SongState Key Laboratory of Military Stomatology, Department of Prosthetic Dentistry, School of Stomatology, Air Force Medical University, Xi'an, People's Republic of China.
Yi CuiEquipment Department, Xijing Hospital, Air Force Medical University, Xi'an, People's Republic of China.
Yang ZhangState Key Laboratory of Military Stomatology, Department of Periodontology, School of Stomatology, Air Force Medical University, Xi'an, People's Republic of China.
Shenglin MeiDepartment of Prosthodontics, College of Stomatology, Xi'an Jiaotong University, Xi'an, People's Republic of China.
Qintao WangState Key Laboratory of Military Stomatology, Department of Periodontology, School of Stomatology, Air Force Medical University, Xi'an, People's Republic of China.
Air Force Medical University · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeReducing toxicity, immunogenicity, and costs of small interfering RNAs (siRNA) carrier materials are key goals for RNA interference (RNAi) technology transition from bench to bed. Recently, calcium ions (Ca

methodsBSA-Ca

resultsBSA and Ca

conclusionBSA-Ca

Indexed as

Gene Transfer TechniquesAdultAnimalsCalciumCell DeathCell DifferentiationEndocytosisHumansMice, Inbred BALB CNanoparticlesOsteogenesisPeriodontal LigamentPeriodontitisRNA, Small InterferingSerum Albumin, BovineSpectroscopy, Fourier Transform InfraredCalciumRNA, Small InterferingSerum Albumin, BovineTumor Necrosis Factor-alphaUbiquitin-Protein LigasesWWP1 protein, humanbovine serum albumincalcium ionsosteogenic differentiationsmall interfering RNA

Identifiers

PMID33262586
PMCPMC7686548
OpenAlexW3098212738

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.