Evidence map›Paper›PMID 33262525›Full record

ArticleLeukemia2021

BCR-ABL1 compound mutants: prevalence, spectrum and correlation with tyrosine kinase inhibitor resistance in a consecutive series of Philadelphia chromosome-positive leukemia patients analyzed by NGS.

Simona Soverini, Margherita Martelli, Luana Bavaro, Caterina De Benedittis, Simona Sica, Federica Sorà, Alessandra Iurlo, Massimiliano Bonifacio, Patrizia Pregno, Sara Galimberti and 14 more

Abstract read
PubMed Publisher
In one paragraph

Article in Leukemia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Resistance mutations in CML and how we approach them.Hematology. American Society of Hematology. Education Program · 2023
    Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Simona SoveriniDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy. simona.soverini@unibo.it.ORCID http://orcid.org/0000-0002-4508-0353
Margherita MartelliDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy.
Luana BavaroDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy.
Caterina De BenedittisDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy.
Simona SicaFondazione Policlinico Universitario A Gemelli-IRCCS, Istituto di Ematologia e Università Cattolica del Sacro Cuore, Rome, Italy.
Federica SoràFondazione Policlinico Universitario A Gemelli-IRCCS, Istituto di Ematologia e Università Cattolica del Sacro Cuore, Rome, Italy.ORCID http://orcid.org/0000-0002-9607-5298
Alessandra IurloHematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0002-4401-0812
Massimiliano BonifacioDepartment of Medicine, Section of Hematology, University of Verona, Verona, Italy.ORCID http://orcid.org/0000-0003-0716-1686
Patrizia PregnoHematology Unit, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza, Turin, Italy.
Sara GalimbertiDepartment of Clinical and Experimental Medicine, Section of Hematology, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0002-4620-0038
Francesca LunghiHematology and BMT Unit, San Raffaele Scientific Institute IRCCS, Milan, Italy.
Francesco AlbanoDepartment of Emergency and Organ Transplantation (D.E.T.O.), Hematology Section, University of Bari, Bari, Italy.ORCID http://orcid.org/0000-0001-7926-6052
Mariella D'AddaHematology Unit, Spedali Civili Azienda Ospedaliera, Brescia, Italy.
Monica CrugnolaDivision of Hematology, Azienda Ospedialiero-Universitaria, Parma, Italy.
Isabella CapodannoHematology Unit, Azienda Unità Sanitaria Locale-IRCCS, Reggio Emilia, Italy.
Fausto CastagnettiAzienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia.
Gabriele GugliottaAzienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia.
Cristina PapayannidisAzienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia.
Gianantonio RostiAzienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia.
Antonio PercesepeUnit of Medical Genetics, University of Parma, Parma, Italy.
Flavio MignoneDepartment of Science and Innovation Technology (DISIT), University of Piemonte Orientale, Alessandria, Italy.
Michele BaccaraniDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy.
Giovanni MartinelliDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy.
Michele CavoAzienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, Bologna, Italia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Resistance, NeoplasmFusion Proteins, bcr-ablHigh-Throughput Nucleotide SequencingHumansLeukemiaPhiladelphia ChromosomePrevalenceProtein Kinase InhibitorsProtein-Tyrosine KinasesBCR-ABL1 fusion protein, humanFusion Proteins, bcr-ablProtein Kinase InhibitorsProtein-Tyrosine Kinases

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.