ArticleNature ecology & evolution2020
Knockout of crustacean leg patterning genes suggests that insect wings and body walls evolved from ancient leg segments.
Article in Nature ecology & evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Genome-wide discovery ofeLife · 2026Article
- Loss, persistence and reversal of phenotypic traits.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Extending Without Extensors: Morphofunctional Insights and Qualitative Experiments on Myriapod Legs.Journal of morphology · 2026Article
- Shared competence forms the basis of gill arch and paired fin serial homology.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
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- Why just fly?Fly · 2025Review
- Gene Expression Analysis Provides Insights Into the Functional and Developmental Differentiations of Pleopodal Lungs in a Terrestrial Isopod Crustacean, Porcellio scaber.Evolution & development · 2025Article
- Quantification of leg mobility in the Burgess Shale Olenoides serratus indicates functional differences between trilobite and xiphosuran appendages.BMC biology · 2025Article
- A new morphological phylogeny of Malacostraca comparing the application of character dependencies and implied weighting.Cladistics : the international journal of the Willi Hennig Society · 2025Article
- Embryonic Development of Appasus japonicus Vuillefroy, With Special Reference to Mouthparts Formation (Insecta: Heteroptera, Belostomatidae).Journal of morphology · 2025Article
- Reduced adult stem cell fate specification led to eye reduction in cave planarians.Nature communications · 2025Article
- From Egg to Adult: A Developmental Table of the Ant Monomorium pharaonis.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2024Article
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- Transcriptional repression and enhancer decommissioning silence cell cycle genes in postmitotic tissues.G3 (Bethesda, Md.) · 2024Article
- A Novel Expression Domain of extradenticle Underlies the Evolutionary Developmental Origin of the Chelicerate Patella.Molecular biology and evolution · 2024Article
- Insect Flight: State of the Field and Future Directions.Integrative and comparative biology · 2024Article
- Evolution of tissue-specific expression of ancestral genes across vertebrates and insects.Nature ecology & evolution · 2024Article
- Transcriptional repression and enhancer decommissioning silence cell cycle genes in postmitotic tissues.bioRxiv : the preprint server for biology · 2024Article
- Lepidopteran prolegs are novel traits, not leg homologs.Science advances · 2023Article
- Cambrian lobopodians shed light on the origin of the tardigrade body plan.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
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No grant is acknowledged in the PubMed record.
Abstract
The origin of insect wings has long been debated. Central to this debate is whether wings are a novel structure on the body wall resulting from gene co-option, or evolved from an exite (outgrowth; for example, a gill) on the leg of an ancestral crustacean. Here, we report the phenotypes for the knockout of five leg patterning genes in the crustacean Parhyale hawaiensis and compare these with their previously published phenotypes in Drosophila and other insects. This leads to an alignment of insect and crustacean legs that suggests that two leg segments that were present in the common ancestor of insects and crustaceans were incorporated into the insect body wall, moving the proximal exite of the leg dorsally, up onto the back, to later form insect wings. Our results suggest that insect wings are not novel structures, but instead evolved from existing, ancestral structures.
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