Evidence map›Paper›PMID 33262445›Full record

Observational studyPediatric research2021

Cerebral oxygenation in preterm infants during maternal singing combined with skin-to-skin care.

Unoke Meder, Eszter Tarjanyi, Kata Kovacs, Eniko Szakmar, Anna Judit Cseko, Timea Hazay, Gusztav Belteki, Miklos Szabo, Agnes Jermendy

Registry-linked trialAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07295106 (Evaluation of the Effects of Personalized Music Therapy on Preterm Infants Admitted to the Neonatal Intensive Care Unit), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07295106 narecruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of the Effects of Personalized Music Therapy on Preterm Infants Admitted to the Neonatal Intensive Care Unit (NICU) and on Parental Stress: A Pilot Randomized Crossover Controlled Trial

TypeinterventionalSponsorFabrizio FainaRan2025 to 2026Enrolled20ConditionsInfant, Premature, Stress, PsychologicalArmsPersonalized Music Therapy (PMT), Quiet Rest
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Impact of Physical Contact on Preterm Infants' Vital Sign Response to Live Music Therapy.International journal of environmental research and public health · 2022
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Unoke Meder1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Eszter Tarjanyi1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Kata Kovacs1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Eniko Szakmar1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Anna Judit Cseko1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Timea Hazay1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Gusztav BeltekiNeonatal Intensive Care Unit, The Rosie Hospital, Cambridge University Hospitals NHS Trust, Cambridge, UK.
Miklos Szabo1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Agnes Jermendy1st Department of Pediatrics, Semmelweis University, Budapest, Hungary. jermendy.agnes@med.semmelweis-univ.hu.
Semmelweis University · HURosie Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur aim was to investigate the effect of music therapy in combination with skin-to-skin care (SSC) on regional cerebral oxygenation (rSO

methodsThis was a prospective single-center observational cohort study conducted in a tertiary neonatal intensive care unit. The study consisted of four phases: (1) baseline measurements in an incubator for 30 min; (2) quiet SSC for 30 min (SSC-Pre); (3) SSC with live maternal singing accompanied by live guitar music for 20 min (SSC-Music); (4) final quiet SSC for another 30 min (SSC-Post).

resultsThe primary outcome measure of mean rSO

conclusionCombining music therapy with SSC appears to be safe in preterm neonates. The impact of the small increase in rSO IMPACT: Music therapy combined with skin-to-skin care (SSC) is safe in clinically stable premature infants and could be encouraged as part of developmental care. This is the first report where near-infrared spectroscopy (NIRS) was used to detect the simultaneous effect of music therapy and SSC on cerebral rSO

Indexed as

Infant, PrematureKangaroo-Mother Care MethodMother-Child RelationsOxygen SaturationSingingBrainFemaleHumansMaleMusic TherapyOutcome Assessment, Health CarePregnancyProspective Studies

Identifiers

PMID33262445
OpenAlexW3107251412

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.