ArticleThe ISME journal2021
Metagenomic analysis reveals a dynamic microbiome with diversified adaptive functions to utilize high lignocellulosic forages in the cattle rumen.
Article in The ISME journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.
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Who cites it
94 citing papers in PubMed, 191 citations in OpenAlex.
- Animal gut microbes and microbiomes in the 21st century and beyond.Science China. Life sciences · 2026Review
- Multi-omics reveals effects of several rumen bacteria on reproductive performance of sheep.Microbiome · 2026Article
- RuSpacer: a CRISPR spacer database derived from ruminant-associated prokaryotes for virome analysis.Scientific reports · 2026Article
- Superior Probiotic Potential of Saccharomyces cerevisiae YH14: In Vitro and In Vivo Evaluation for Animal Nutrition and Health.Probiotics and antimicrobial proteins · 2026Article
- The Seasonal Dietary Shift and Niche Resilience of Yaks on the Qinghai-Tibetan Plateau.Animals : an open access journal from MDPI · 2026Article
- Effects of Glycerol Fatty Acid Esters on Growth Performance, Methane Emissions, and Rumen Microbial Flora of Dabieshan Beef Cattle.Veterinary sciences · 2026Article
- How Habitat Micromodification Influences Gut Microbiota and Diet Composition of Reintroduced Species: Evidence from Endangered Père David's Deer.Microorganisms · 2026Article
- Ruminal archaea and bacteria metatranscriptomic responses to supplementation in steers fed low-quality forage.Journal of animal science · 2026Article
- Effects of Diet and Altitude on the Microbiota of the First Compartment of the Stomach in Peruvian Alpacas in Highland Puna Regions and Their Correlations with Blood Parameters.Microorganisms · 2026Article
- Functional fiber supplementation improves reproductive performance in sows by reshaping gut microbial functions related to immunity and metabolic health.Frontiers in veterinary science · 2026Article
- Maternal supplementation of functional fiber improves reproduction performance by modulating gut microbiota during pregnancy.Frontiers in microbiology · 2026Article
- BileActome reveals community-assembled bile acid metabolism in the rumen microbiome.ISME communications · 2026Article
- Metagenomic analysis of fecal and environmental microbiota in rural mixed livestock farming systems in South Africa.Frontiers in cellular and infection microbiology · 2026Article
- Effects of Rumen-Protected β-Alanine on Growth Performance, Rumen Microbiome, and Serum Metabolome of Beef Cattle.Animals : an open access journal from MDPI · 2025Article
- Effects of Sea Buckthorn Polysaccharides on Rumen In Vitro Fermentation Characteristics and Microbial Composition of Hu Sheep.Microorganisms · 2025Article
- Revealing the adaptive metabolic differences of different sheep breeds in plateau areas based on the Gut-Cardiac axis.BMC genomics · 2025Article
- Transport stress alters serum biochemistry and gut microbiota in Tibetan sheep (ovis aries): a 30-day recovery assessment.BMC microbiology · 2025Article
- Effects of selenium and anthocyanin on apparent digestibility, blood parameters, rumen fermentation, and microbiota compositions of goat doe.Scientific reports · 2025Article
- Heated drinking water in winter improves growth performance of male Hu sheep by modulating rumen quorum sensing and metabolites, and enhancing serum antioxidant capacity.Animal bioscience · 2025Article
- Multi-omics reveal the gut microbiota-mediated severe foraging environment adaption of small wild ruminants in the Three-River-Source National Park, China.Integrative zoology · 2025Article
34 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 5 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rumen microbiota play a key role in the digestion and utilization of plant materials by the ruminant species, which have important implications for greenhouse gas emission. Yet, little is known about the key taxa and potential gene functions involved in the digestion process. Here, we performed a genome-centric analysis of rumen microbiota attached to six different lignocellulosic biomasses in rumen-fistulated cattle. Our metagenome sequencing provided novel genomic insights into functional potential of 523 uncultured bacteria and 15 mostly uncultured archaea in the rumen. The assembled genomes belonged mainly to Bacteroidota, Firmicutes, Verrucomicrobiota, and Fibrobacterota and were enriched for genes related to the degradation of lignocellulosic polymers and the fermentation of degraded products into short chain volatile fatty acids. We also found a shift from copiotrophic to oligotrophic taxa during the course of rumen fermentation, potentially important for the digestion of recalcitrant lignocellulosic substrates in the physiochemically complex and varying environment of the rumen. Differential colonization of forages (the incubated lignocellulosic materials) by rumen microbiota suggests that taxonomic and metabolic diversification is an evolutionary adaptation to diverse lignocellulosic substrates constituting a major component of the cattle's diet. Our data also provide novel insights into the key role of unique microbial diversity and associated gene functions in the degradation of recalcitrant lignocellulosic materials in the rumen.
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