ArticleScientific reports2020
Control of response interference: caudate nucleus contributes to selective inhibition.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? - a systematic review.Journal of child psychology and psychiatry, and allied disciplines · 2025Pooled it
- Success versus failure in cognitive control: Meta-analytic evidence from neuroimaging studies on error processing.Neuroscience and biobehavioral reviews · 2024Pooled it
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- The yes-no reversal phenomenon in patients with primary progressive apraxia of speech.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Neural underpinnings of ethical decisions in life and death dilemmas in naïve and expert firefighters.Scientific reports · 2024Article
- A Multilevel Examination of Cognitive Control in Adolescents With Nonsuicidal Self-injury.Biological psychiatry global open science · 2023Article
- Mechanisms and neuroanatomy of response selection in tool and non-tool action tasks: Evidence from left-hemisphere stroke.Cortex; a journal devoted to the study of the nervous system and behavior · 2023Article
- Association of Circumscribed Subcortical Gray and White Matter Lesions With Apraxic Deficits in Patients With Left Hemisphere Stroke.Neurology · 2023Article
- Do after "not to do": Deinhibition in cognitive control.Memory & cognition · 2023Article
- Atrophy in subcortical gray matter in adult patients with moyamoya disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Cognitive flexibility: neurobehavioral correlates of changing one's mind.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- A circuit-based approach to modulate hypersexuality in Parkinson's disease.Psychiatry and clinical neurosciences · 2023Article
- Prefrontal Cortex Hemodynamics and Functional Connectivity Changes during Performance Working Memory Tasks in Older Adults with Sleep Disorders.Brain sciences · 2023Article
- Neural substrates of continuous and discrete inhibitory control.Translational psychiatry · 2023Article
- Sex and strategy effects on brain activation during a 3D-navigation task.Communications biology · 2022Article
- Psychopathic tendency in violent offenders is associated with reduced aversive Pavlovian inhibition of behavior and associated striatal BOLD signal.Frontiers in behavioral neuroscience · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While the role of cortical regions in cognitive control processes is well accepted, the contribution of subcortical structures (e.g., the striatum), especially to the control of response interference, remains controversial. Therefore, the present study aimed to investigate the cortical and particularly subcortical neural mechanisms of response interference control (including selective inhibition). Thirteen healthy young participants underwent event-related functional magnetic resonance imaging while performing a unimanual version of the Simon task. In this task, successful performance required the resolution of stimulus-response conflicts in incongruent trials by selectively inhibiting interfering response tendencies. The behavioral results show an asymmetrical Simon effect that was more pronounced in the contralateral hemifield. Contrasting incongruent trials with congruent trials (i.e., the overall Simon effect) significantly activated clusters in the right anterior cingulate cortex, the right posterior insula, and the caudate nucleus bilaterally. Furthermore, a region of interest analysis based on previous patient studies revealed that activation in the bilateral caudate nucleus significantly co-varied with a parameter of selective inhibition derived from distributional analyses of response times. Our results corroborate the notion that the cognitive control of response interference is supported by a fronto-striatal circuitry, with a functional contribution of the caudate nucleus to the selective inhibition of interfering response tendencies.
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