ReviewNature communications2020
Towards a unified open access dataset of molecular interactions.
Abstract readReview
In one paragraph
Review in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed.
- Network Analysis to Identify MicroRNAs Involved in Alzheimer's Disease and to Improve Drug Prioritization.Biomedicines · 2026Article
- Mass Spectrometry Proteomics: A Key to Faster Drug Discovery.Journal of medicinal chemistry · 2026Review
- Interactomics: Dissecting Protein Networks in Living Systems.Advances in experimental medicine and biology · 2026Review
- A guide to building the matrisome interactome: from computational predictions to experimental validation.The FEBS journal · 2026Review
- ODin (Orthology Data driven Interaction) Predictor: A Client‑Side Web Application for Unveiling Biological Connections Through Orthology from Alliance of Genome Resources.microPublication biology · 2026Article
- Article
- Multi-scale classification decodes the complexity of the human E3 ligome.Nature communications · 2025Article
- Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery.Proteomics · 2025Review
- Pentacyclic Triterpenoid Maslinic Acid Promotes Hair Growth Comparable to Minoxidil: A New Insight on the Potential Involvement of Cilia Activity.ACS pharmacology & translational science · 2025Article
- Unravelling the human taste receptor interactome: machine learning and molecular modelling insights into protein-protein interactions.NPJ science of food · 2025Article
- What Have Data Standards Ever Done for Us?Molecular & cellular proteomics : MCP · 2025Review
- Contextualizing molecular and structural aging across human organs.medRxiv : the preprint server for health sciences · 2025Article
- In-silico discovery of type-2 diabetes-causing host key genes that are associated with the complexity of monkeypox and repurposing common drugs.Briefings in bioinformatics · 2025Article
- Co-Deposited Proteins in Alzheimer's Disease as a Potential Treasure Trove for Drug Repurposing.Molecules (Basel, Switzerland) · 2025Article
- Standardized pipelines support and facilitate integration of diverse datasets at the Rat Genome Database.Database : the journal of biological databases and curation · 2025Article
- Structure-Based Approaches for Protein-Protein Interaction Prediction Using Machine Learning and Deep Learning.Biomolecules · 2025Review
- Integrated Analysis of microRNA Targets Reveals New Insights into Transcriptional-Post-Transcriptional Regulatory Cross-Talk.Biology · 2025Article
- Complex portal 2025: predicted human complexes and enhanced visualisation tools for the comparison of orthologous and paralogous complexes.Nucleic acids research · 2025Article
- Article
- Functional implications of glycans and their curation: insights from the workshop held at the 16th Annual International Biocuration Conference in Padua, Italy.Database : the journal of biological databases and curation · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors.
Pablo PorrasEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Campus, Hinxton, Cambridge, CB10 1SD, UK.ORCID 0000-0002-8429-8793
Elisabet BarreraEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Campus, Hinxton, Cambridge, CB10 1SD, UK.
Alan BridgeSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 rue Michel Servet, CH-1211, Geneva, Switzerland.
Noemi Del-ToroEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Campus, Hinxton, Cambridge, CB10 1SD, UK.ORCID 0000-0001-5272-7613
Gianni CesareniUniversity of Rome Tor Vergata, Rome, Italy.ORCID 0000-0002-9528-6018
Margaret DuesburyEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Campus, Hinxton, Cambridge, CB10 1SD, UK.
Henning HermjakobEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Campus, Hinxton, Cambridge, CB10 1SD, UK.ORCID 0000-0001-8479-0262
Marta IannuccelliUniversity of Rome Tor Vergata, Rome, Italy.ORCID 0000-0002-2374-3531
Igor JurisicaOsteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute, and Krembil Research Institute, University Health Network, 60 Leonard Avenue, 5KD-407, Toronto, ON, M5T 0S8, Canada.
Max KotlyarOsteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute, and Krembil Research Institute, University Health Network, 60 Leonard Avenue, 5KD-407, Toronto, ON, M5T 0S8, Canada.
Luana LicataUniversity of Rome Tor Vergata, Rome, Italy.ORCID 0000-0001-5084-9000
Ruth C LoveringFunctional Gene Annotation, Preclinical and Fundamental Science, UCL Institute of Cardiovascular Science, University College London, London, WC1E 6JF, UK.ORCID 0000-0002-9791-0064
David J LynnComputational and Systems Biology Program, Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA, 5000, Australia.ORCID 0000-0003-4664-1404
Birgit MeldalEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Campus, Hinxton, Cambridge, CB10 1SD, UK.ORCID 0000-0003-4062-6158
Bindu NanduriInstitute for Genomics, Biocomputing and Biotechnology, Mississippi State University, Starkville, MS, USA.
Kalpana PaneerselvamEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Campus, Hinxton, Cambridge, CB10 1SD, UK.
Simona PanniUniversità della Calabria, Dipartimento di Biologia, Ecologia e Scienze della Terra, Via Pietro Bucci Cubo 6/C, Rende, CS, Italy.ORCID 0000-0002-7500-4028
Chiara PastrelloOsteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute, and Krembil Research Institute, University Health Network, 60 Leonard Avenue, 5KD-407, Toronto, ON, M5T 0S8, Canada.ORCID 0000-0002-1934-7472
Matteo PellegriniDepartment of Molecular, Cell and Developmental Biology, UCLA, Box 951606, Los Angeles, CA, 90095-1606, USA.
Livia PerfettoEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Campus, Hinxton, Cambridge, CB10 1SD, UK.
Negin RahimzadehUCLA-DOE Institute, University of California, Los Angeles, CA, 90095, USA.
Prashansa RatanUCLA-DOE Institute, University of California, Los Angeles, CA, 90095, USA.
Sylvie Ricard-BlumICBMS, UMR 5246 University Lyon 1 - CNRS, Univ. Lyon, 69622, Villeurbanne, France.ORCID 0000-0001-9263-1851
Lukasz SalwinskiUCLA-DOE Institute, University of California, Los Angeles, CA, 90095, USA.ORCID 0000-0003-4522-1969
Gautam ShirodkarUCLA-DOE Institute, University of California, Los Angeles, CA, 90095, USA.
Anjalia ShrivastavaEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Campus, Hinxton, Cambridge, CB10 1SD, UK.ORCID 0000-0002-7471-2663
Sandra OrchardEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Campus, Hinxton, Cambridge, CB10 1SD, UK. orchard@ebi.ac.uk.ORCID 0000-0002-8878-3972
Funding
UniProt - Text Mining and Large Language models to Enhance Functional Annotation in UniProt of Protein Variants Associated with Alzheimer's DiseaseU24HG007822 · NHGRI · GEORGETOWN UNIVERSITY · PI Alex Bateman, Alan James Bridge · 2018 to 2026
$53.0MENHANCING THE INTERNATIONAL MOLECULAR EXCHANGE (IMEX): PROVIDING AN IMPROVED COMMUNITY-ORIENTED MOLECULAR INTERACTIONS RESOURCER01GM123126 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PELLEGRINI, MATTEO · 2018 to 2021
$2.0MCIHRNHGRI NIH HHS U24 HG007822NIGMS NIH HHS R01 GM123126Wellcome TrustWellcome Trust 3367
Abstract
The International Molecular Exchange (IMEx) Consortium provides scientists with a single body of experimentally verified protein interactions curated in rich contextual detail to an internationally agreed standard. In this update to the work of the IMEx Consortium, we discuss how this initiative has been working in practice, how it has ensured database sustainability, and how it is meeting emerging annotation challenges through the introduction of new interactor types and data formats. Additionally, we provide examples of how IMEx data are being used by biomedical researchers and integrated in other bioinformatic tools and resources.
Indexed as
Access to InformationDatabases, GeneticHumansInformation DisseminationInternational Cooperation
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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.