Evidence map›Paper›PMID 33262093›Full record

ArticleEuropean journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery2021

Vascular Surgery During COVID-19 Emergency in Hub Hospitals of Lombardy: Experience on 305 Patients.

Andrea Kahlberg, Daniele Mascia, Raffaello Bellosta, Luca Attisani, Matteo Pegorer, Anna M Socrate, Matteo Ferraris, Piero Trabattoni, Enrico Rinaldi, Andrea Melloni and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  6. Acute Limb Ischemia in COVID-19: A Systematic Review.The International journal of angiology : official publication of the International College of Angiology, Inc · 2023
    Review
  7. Review
  8. Editor's Choice - Outcomes of Surgery for Patients with Peripheral Arterial Disease During the COVID-19 Pandemic in the United Kingdom: A Population Based Study.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Limb Fasciotomy for COVID-19 Patients: Is the Chance to Cut a Chance to Cure?Plastic and reconstructive surgery. Global open · 2022
    Article
  14. Review
  15. SARS-CoV-2 testing in patients with low COVID-19 suspicion at admission to a tertiary care hospital, Stockholm, Sweden, March to September 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Article
  16. Review
  17. Article
  18. Maintaining Safe Elective Aneurysm Surgery in the COVID-19 Era.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2021
    Article
  19. Observational
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Andrea KahlbergVascular Surgery, Vita-Salute University, IRCCS San Raffaele Scientific Institute, Milan, Italy. Electronic address: kahlberg.andrea@hsr.it.
Daniele MasciaVascular Surgery, Vita-Salute University, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Raffaello BellostaVascular Surgery, Department Cardiovascular Surgery, Fondazione Poliambulanza, Brescia, Italy.
Luca AttisaniVascular Surgery, Department Cardiovascular Surgery, Fondazione Poliambulanza, Brescia, Italy.
Matteo PegorerVascular Surgery, Department Cardiovascular Surgery, Fondazione Poliambulanza, Brescia, Italy.
Anna M SocrateVascular Surgery, ASST Ovest Milano, Legnano, Italy.
Matteo FerrarisVascular Surgery, ASST Ovest Milano, Legnano, Italy.
Piero TrabattoniDepartment of Cardiovascular Disease, Vascular Surgery Unit, IRCCS Centro Cardiologico Monzino, Milan, Italy.
Enrico RinaldiVascular Surgery, Vita-Salute University, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Andrea MelloniVascular Surgery, Vita-Salute University, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Fabrizio MonacoDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Germano MelissanoVascular Surgery, Vita-Salute University, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Roberto ChiesaVascular Surgery, Vita-Salute University, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Vita-Salute San Raffaele University · ITFondazione Poliambulanza Istituto Ospedaliero · ITASST Melegnano e della Martesana · ITCentro Cardiologico Monzino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDuring the most aggressive phase of the COVID-19 outbreak in Italy, the Regional Authority of Lombardy identified a number of hospitals, named Hubs, chosen to serve the whole region for highly specialised cases, including vascular surgery. This study reports the experience of the four Hubs for Vascular Surgery in Lombardy and provides a comparison of in hospital mortality and major adverse events (MAEs) according to COVID-19 testing.

methodsData from all patients who were referred to the Vascular Surgery Department of Hubs from 9 March to 28 April 2020 were collected prospectively and analysed. A positive COVID-19 polymerase chain reaction swab test, or symptoms (fever > 37.5 °C, upper respiratory tract symptoms, chest pain, and contact/travel history) associated with interstitial pneumonia on chest computed tomography scan were considered diagnostic of COVID-19 disease. Patient characteristics, operative variables, and in hospital outcomes were compared according to COVID-19 testing. A multivariable model was used to identify independent predictors of in hospital death and MAEs.

resultsAmong 305 included patients, 64 (21%) tested positive for COVID-19 (COVID group) and 241 (79%) did not (non-COVID group). COVID patients presented more frequently with acute limb ischaemia than non-COVID patients (64% vs. 23%; p < .001) and had a significantly higher in hospital mortality (25% vs. 6%; p < .001). Clinical success, MAEs, re-interventions, and pulmonary and renal complications were significantly worse in COVID patients. Independent risk factors for in hospital death were COVID (OR 4.1), medical treatment (OR 7.2), and emergency setting (OR 13.6). COVID (OR 3.4), obesity class V (OR 13.5), and emergency setting (OR 4.0) were independent risk factors for development of MAEs.

conclusionDuring the COVID-19 pandemic in Lombardy, acute limb ischaemia was the most frequent vascular disease requiring surgical treatment. COVID-19 was associated with a fourfold increased risk of death and a threefold increased risk of major adverse events.

Indexed as

COVID-19Infection ControlPostoperative ComplicationsVascular DiseasesVascular Surgical ProceduresAgedCOVID-19 TestingEmergenciesEmergency Service, HospitalFemaleHospital MortalityHumansItalyMaleOutcome and Process Assessment, Health CarePrognosisCovid-19Limb ischaemiaLombardyPandemicsSARS-CoV-2Vascular surgery

Identifiers

PMID33262093
PMCPMC7664352
OpenAlexW3104475505

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.