Evidence map›Paper›PMID 33262076›Full record

SynthesisPulmonology

Respiratory function in patients post-infection by COVID-19: a systematic review and meta-analysis.

R Torres-Castro, L Vasconcello-Castillo, X Alsina-Restoy, L Solis-Navarro, F Burgos, H Puppo, J Vilaró

5 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Pulmonology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 291 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
291citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04826731 completednot on this map

Effect of Respiratory Exerciser on Pulmonary Functions of COVID-19 Patients, A Prospective Observational Study

TypeobservationalSponsorDiskapi Yildirim Beyazit Education and Research HospitalRan2021 to 2021Enrolled14ConditionsCovid19, Respiratory Function Loss, Coronavirus Infection, Pneumonia, ViralArmsIncentive Spirometer/Respiratory Exerciser
NCT05249842 completednot on this map

Respiratory Function 3 Months After Hospital Discharge in Critically Ill COVID-19 Patients

TypeobservationalSponsorHospital Sao DomingosRan2020 to 2022Enrolled60ConditionsCOVID-19ArmsSpirometric evaluation, Physical component summary, 6MWT
NCT05386485 unknown statusnot on this map

FUNCTION Study: Follow- Up Study iN SARS-CoV-2 infecTION. Long-term Impact on Cardiopulmonary Function and Quality of Life in Patients Recovered From SARS-CoV-2 Infection in Lima, Peru

TypeobservationalSponsorUniversidad Peruana Cayetano HerediaRan2021 to 2022Enrolled162ConditionsCOVID-19ArmsNone intervation
NCT05770440 unknown statusnot on this map

Impact of COVID-19 on Lung Function in COPD Patients

TypeobservationalSponsorFundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaRan2023 to 2025Enrolled250ConditionsCOPD, COVID-19
NCT05967039 unknown statusnot on this map

Evaluation of Lung Function, Lung Ultrasound and Functional Capacity in Long-COVID Patients Who Underwent Physical Therapy

TypeobservationalSponsorCentro Universitário Augusto MottaRan2022 to 2023Enrolled65ConditionsPost-COVID-19 Syndrome, Long COVIDArmsPhysiotherapy
3 · Its place in the literature

Who cites it

291 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
  2. Does ambient PMBMC medicine · 2025
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  4. Recovery of lung function during the first year after COVID-19: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
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231 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

R Torres-CastroDepartment of Physical Therapy, Faculty of Medicine, University of Chile, Santiago, Chile; International Physiotherapy Research Network (PhysioEvidence). Electronic address: klgorodrigotorres@gmail.com.
L Vasconcello-CastilloDepartment of Physical Therapy, Faculty of Medicine, University of Chile, Santiago, Chile; International Physiotherapy Research Network (PhysioEvidence).
X Alsina-RestoyServei de Pneumologia, Institut Clínic Respiratori, Hospital Clinic de Barcelona, Universitat de Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
L Solis-NavarroDepartment of Physical Therapy, Faculty of Medicine, University of Chile, Santiago, Chile.
F BurgosServei de Pneumologia, Institut Clínic Respiratori, Hospital Clinic de Barcelona, Universitat de Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Center for Biomedical Network Research in Respiratory Diseases (CIBERES), Spain.
H PuppoDepartment of Physical Therapy, Faculty of Medicine, University of Chile, Santiago, Chile; International Physiotherapy Research Network (PhysioEvidence).
J VilaróInternational Physiotherapy Research Network (PhysioEvidence); Blanquerna School of Health Sciences, Global Research on Wellbeing (GRoW), Universitat Ramon Llull, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence suggests lungs as the organ most affected by coronavirus disease 2019 (COVID-19). The literature on previous coronavirus infections reports that patients may experience persistent impairment in respiratory function after being discharged. Our objective was to determine the prevalence of restrictive pattern, obstructive pattern and altered diffusion in patients post-COVID-19 infection and to describe the different evaluations of respiratory function used with these patients.

methodsA systematic review was conducted in five databases. Studies that used lung function testing to assess post-infection COVID-19 patients were included for review. Two independent reviewers analysed the studies, extracted the data and assessed the quality of evidence.

resultsOf the 1973 reports returned by the initial search, seven articles reporting on 380 patients were included in the data synthesis. In the sensitivity analysis, we found a prevalence of 0.39 (CI 0.24-0.56, p < 0.01, I

conclusionPost-infection COVID-19 patients showed impaired lung function; the most important of the pulmonary function tests affected was the diffusion capacity.

Indexed as

COVID-19Forced Expiratory VolumeHumansLungPost-Acute COVID-19 SyndromePulmonary Diffusing CapacityRespiratory Function TestsSARS-CoV-2Total Lung CapacityVital CapacityCOVID-19Lung function testMeta-analysisRespiratory functionRespiratory musclesSystematic review

Identifiers

PMID33262076
PMCPMC7687368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.