Evidence map›Paper›PMID 33261978›Full record

SynthesisClinical oncology (Royal College of Radiologists (Great Britain))2021

Clinical Characteristics and Outcomes in Patients with COVID-19 and Cancer: a Systematic Review and Meta-analysis.

P Zarifkar, A Kamath, C Robinson, N Morgulchik, S F H Shah, T K M Cheng, C Dominic, A O Fehintola, G Bhalla, T Ahillan and 8 more

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical oncology (Royal College of Radiologists (Great Britain)), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Coronavirus Disease 2019 Vaccination for Cancer Patients: Risk or Benefit?Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Pooled it
  3. Article
  4. Observational
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Remdesivir-Associated Survival Outcomes Among Immunocompromised Patients Hospitalized for COVID-19: Real-world Evidence From the Omicron-Dominant Era.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  10. Article
  11. Article
  12. Review
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  14. Article
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 15 institutions in 4 countries.

P ZarifkarDepartment of Nuclear Medicine and PET, Aarhus University Hospital, Aarhus, Denmark. Electronic address: pardis.zarifkar@post.au.dk.
A KamathFaculty of Medicine, University of Oxford, Medical Sciences Divisional Office, University of Oxford, John Radcliffe Hospital, Oxford, UK.
C RobinsonFaculty of Medicine, University of Oxford, Medical Sciences Divisional Office, University of Oxford, John Radcliffe Hospital, Oxford, UK.
N MorgulchikImperial College London, Department of Chemistry, Molecular Sciences Research Hub, London, UK.
S F H ShahSchool of Clinical Medicine, University of Cambridge, Cambridge, UK.
T K M ChengSchool of Clinical Medicine, University of Cambridge, Cambridge, UK.
C DominicBarts and the London School of Medicine, Queen Mary University of London, London, UK.
A O FehintolaCollege of Medicine, University of Ibadan, Ibadan, Nigeria.
G BhallaBarts and the London School of Medicine, Queen Mary University of London, London, UK.
T AhillanUniversity College London Medical School, London, UK.
L Mourgue d'AlgueUniversity College London, Faculty of Life Sciences, London, UK.
J LeeNuffield Department of Primary Care Health Sciences, Oxford University, Oxford, UK.
A PareekDepartment of Radiology Stanford University School of Medicine, Stanford, California, USA.
M CareyDepartment of Palliative Care Oxford University Hospitals NHS Foundation Trust, Sobell House Hospice, Churchill Hospital, Oxford, UK.
D J HughesDepartment of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
M MillerDepartment of Palliative Care Oxford University Hospitals NHS Foundation Trust, Sobell House Hospice, Churchill Hospital, Oxford, UK.
V K WoodcockDepartment of Oncology, Churchill Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.
M ShrotriLondon School of Hygiene & Tropical Medicine, London, UK.
Queen Mary University of London · GBUniversity of Cambridge · GBUniversity of Oxford · GBAarhus University Hospital · DKChurchill Hospital · GBFaculty (United Kingdom) · GBImperial College London · GBJohn Radcliffe Hospital · GBKing's College London · GBLondon School of Hygiene & Tropical Medicine · GBOxford University Hospitals NHS Trust · GBSobell House · GBStanford University · USUniversity College London · GBUniversity of Ibadan · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Much of routine cancer care has been disrupted due to the perceived susceptibility to SARS-CoV-2 infection in cancer patients. Here, we systematically review the current evidence base pertaining to the prevalence, presentation and outcome of COVID-19 in cancer patients, in order to inform policy and practice going forwards. A keyword-structured systematic search was conducted on Pubmed, Cochrane, Embase and MedRxiv databases for studies reporting primary data on COVID-19 in cancer patients. Studies were critically appraised using the NIH National Heart, Lung and Blood Institute's quality assessment tool set. The pooled prevalence of cancer as a co-morbidity in patients with COVID-19 and pooled in-hospital mortality risk of COVID-19 in cancer patients were derived by random-effects meta-analyses. In total, 110 studies from 10 countries were included. The pooled prevalence of cancer as a co-morbidity in hospitalised patients with COVID-19 was 2.6% (95% confidence interval 1.8%, 3.5%, I

Indexed as

COVID-19NeoplasmsComorbidityHumansPrevalenceSARS-CoV-2Treatment OutcomeCancerCOVID-19mortalityprevalenceSARS-CoV-2systematic review

Identifiers

PMID33261978
PMCPMC7674130
OpenAlexW3104443624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.