Evidence map›Paper›PMID 33261221›Full record

ArticleToxins2020

Gymnodimine A and 13-desMethyl Spirolide C Alter Intracellular Calcium Levels via Acetylcholine Receptors.

Joyce A Nieva, Bernd Krock, Urban Tillmann, Jan Tebben, Christian Zurhelle, Ulf Bickmeyer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joyce A NievaAlfred Wegener Institute, Helmholtz Center for Polar and Marine Research, D-27570 Bremerhaven, Germany.
Bernd KrockAlfred Wegener Institute, Helmholtz Center for Polar and Marine Research, D-27570 Bremerhaven, Germany.
Urban TillmannAlfred Wegener Institute, Helmholtz Center for Polar and Marine Research, D-27570 Bremerhaven, Germany.ORCID 0000-0002-8207-4382
Jan TebbenAlfred Wegener Institute, Helmholtz Center for Polar and Marine Research, D-27570 Bremerhaven, Germany.
Christian ZurhelleAlfred Wegener Institute, Helmholtz Center for Polar and Marine Research, D-27570 Bremerhaven, Germany.
Ulf BickmeyerAlfred Wegener Institute, Helmholtz Center for Polar and Marine Research, D-27570 Bremerhaven, Germany.
Alfred-Wegener-Institut Helmholtz-Zentrum für Polar- und Meeresforschung · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gymnodimines and spirolides are cyclic imine phycotoxins and known antagonists of nicotinic acetylcholine receptors (nAChRs). We investigated the effect of gymnodimine A (GYM A) and 13-desmethyl spirolide C (SPX 1) from

Indexed as

AnimalsCalciumCalcium ChannelsCalcium SignalingCell LineDinoflagellidaHeterocyclic Compounds, 4 or More RingsIminesMarine ToxinsMuscarinic AntagonistsNicotinic AgonistsPC12 CellsRatsReceptors, MuscarinicReceptors, NicotinicSpiro Compounds13-desmethylspirolide CCalciumCalcium Channelsgymnodimine AHeterocyclic Compounds, 4 or More RingsIminesMarine ToxinsMuscarinic AntagonistsNicotinic AgonistsReceptors, MuscarinicReceptors, NicotinicSpiro CompoundsAlexandrium ostenfeldiicalcium signalingcyclic iminenicotinic, muscarinic, and acetylcholine receptors

Identifiers

PMID33261221
PMCPMC7760841
OpenAlexW3110426384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.