Evidence map›Paper›PMID 33261019›Full record

ArticleNutrients2020

Epidemiology of Hypoalbuminemia in Hospitalized Patients: A Clinical Matter or an Emerging Public Health Problem?

Stefania Moramarco, Laura Morciano, Luca Morucci, Mario Messinese, Paola Gualtieri, Mariachiara Carestia, Fausto Ciccacci, Stefano Orlando, Ersilia Buonomo, Jacopo Maria Legramante and 2 more

Abstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Exploratory model-based optimizing isavuconazole dosing regimens forFrontiers in cellular and infection microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stefania MoramarcoSection of Hygiene and Public Health, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.ORCID 0000-0001-6192-8775
Laura MorcianoSection of Hygiene and Public Health, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.
Luca MorucciSection of Hygiene and Public Health, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.
Mario MessineseSection of Hygiene and Public Health, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.
Paola GualtieriSection of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.ORCID 0000-0003-1533-4276
Mariachiara CarestiaSection of Hygiene and Public Health, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.ORCID 0000-0001-7811-5201
Fausto CiccacciUnicamillus, International Medical University in Rome, Via di Sant'Alessandro, 8-00131 Rome, Italy.ORCID 0000-0003-0262-707X
Stefano OrlandoSection of Hygiene and Public Health, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.ORCID 0000-0001-9706-4075
Ersilia BuonomoSection of Hygiene and Public Health, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.
Jacopo Maria LegramanteDepartment of Systems Medicine, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.
Antonino De LorenzoSection of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.ORCID 0000-0001-6524-4493
Leonardo PalombiSection of Hygiene and Public Health, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1-00133 Rome, Italy.ORCID 0000-0003-1806-5278

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum albumin levels are strongly associated with the morbidity, prognosis, and mortality rates of patients with hypoalbuminemia, which is a frequent problem during hospitalization. An observational retrospective study was carried out to analyze changes in albumin levels in hospitalized patients at the "Fondazione Policlinico Tor Vergata-PTV" in 2018. The prevalence of preexisting hypoalbuminemia at the time of discharge from hospital was investigated using a sample of 9428 patients. Information was collected from the discharge files recorded in the central informatics system of the hospital. Analysis of albumin levels at admission and at discharge was conducted by classes of albuminemia and then stratified by age. At the time of admission, hypoalbuminemia was found to be present in more than half of the sample, with no sex differences. The serum albumin level tended to decrease with age, with pathologic levels appearing from 50 years and progressive worsening thereafter. The condition of marked and mild hypoalbuminemia was more prevalent in patients over 65 years of age. Our findings suggest that hypoalbuminemia should be considered a dangerous condition in itself and a serious public health problem. We aimed to emphasize the role of albumin as useful marker of the in-hospital malnutrition and frailty, to be integrated in the routinely assessment of patients for reconsidering ad hoc healthcare pathways after discharge from hospital, especially when dealing with fragile populations.

Indexed as

AdultAgedFemaleHumansHypoalbuminemiaInpatientsMaleMiddle AgedPublic HealthRisk FactorsSerum AlbuminSerum Albuminelderlyfragile populationshospitalizationhypoalbuminemiapublic healthserum albumin

Identifiers

PMID33261019
PMCPMC7760225

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.