Evidence map›Paper›PMID 33260948›Full record

ArticleInternational journal of molecular sciences2020

New Formulation of a Methylseleno-Aspirin Analog with Anticancer Activity towards Colon Cancer.

Ana Carolina Ruberte, Gustavo González-Gaitano, Arun K Sharma, Carlos Aydillo, Ignacio Encío, Carmen Sanmartín, Daniel Plano

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Following the Trace of Cyclodextrins on the Selenium and Tellurium Odyssey.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Formulation Studies with Cyclodextrins for Novel Selenium NSAID Derivatives.International journal of molecular sciences · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ana Carolina RuberteDepartment of Pharmaceutical Technology and Chemistry, University of Navarra, Irunlarrea 1, E-31008 Pamplona, Spain.ORCID 0000-0001-8818-3136
Gustavo González-GaitanoDepartment of Chemistry, University of Navarra, 31080 Pamplona, Spain.ORCID 0000-0002-1477-6710
Arun K SharmaDepartment of Pharmacology, Penn State Cancer Institute, CH72, Penn State College of Medicine, Hershey, PA 17036, USA.
Carlos AydilloDepartment of Pharmaceutical Technology and Chemistry, University of Navarra, Irunlarrea 1, E-31008 Pamplona, Spain.ORCID 0000-0002-0542-967X
Ignacio EncíoInstituto de Investigación Sanitaria de Navarra (IdiSNA), Irunlarrea 3, E-31008 Pamplona, Spain.ORCID 0000-0003-1732-1989
Carmen SanmartínDepartment of Pharmaceutical Technology and Chemistry, University of Navarra, Irunlarrea 1, E-31008 Pamplona, Spain.ORCID 0000-0003-3431-7826
Daniel PlanoDepartment of Pharmaceutical Technology and Chemistry, University of Navarra, Irunlarrea 1, E-31008 Pamplona, Spain.ORCID 0000-0002-8266-0445
Navarre Institute of Health Research · ESPenn State Milton S. Hershey Medical Center · USUniversidad de Navarra · ES

Funding

Universidad de Navarra (PIUNA) 2018-21Universidad Nacional de Educación a Distancia (UNED) P/12/19
6 · The paper itself

Abstract

Aspirin (ASA) has attracted wide interest of numerous scientists worldwide thanks to its chemopreventive and chemotherapeutic effects, particularly in colorectal cancer (CRC). Incorporation of selenium (Se) atom into ASA has greatly increased their anti-tumoral efficacy in CRC compared with the organic counterparts without the Se functionality, such as the promising antitumoral methylseleno-ASA analog (

Indexed as

Antineoplastic AgentsAspirinbeta-CyclodextrinsCell ProliferationColonic NeoplasmsDrug LiberationHT29 CellsHumansMicellesPoloxamerProton Magnetic Resonance SpectroscopySolubilitySpectrometry, FluorescenceWaterAntineoplastic AgentsAspirinbeta-CyclodextrinsbetadexMicellesPoloxamerWateraspirincolorectal cancercyclodextrinscytotoxicityPluronicselenium

Identifiers

PMID33260948
PMCPMC7730823
OpenAlexW3107158567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.