Evidence map›Paper›PMID 33260897›Full record

ArticleCancers2020

Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma in Asia Frequently Shows

Sakura Tomita, Yara Yukie Kikuti, Joaquim Carreras, Rika Sakai, Katsuyoshi Takata, Tadashi Yoshino, Silvia Bea, Elias Campo, Edoardo Missiaglia, Justine Bouilly and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Surface CD3-negative monomorphic epitheliotropic intestinal T-cell lymphoma.Journal of clinical and experimental hematopathology : JCEH · 2022
    Article
  12. Article
  13. Review
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  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Sakura TomitaDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Kanagawa, Isehara 259-1193, Japan.ORCID 0000-0003-3358-5845
Yara Yukie KikutiDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Kanagawa, Isehara 259-1193, Japan.
Joaquim CarrerasDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Kanagawa, Isehara 259-1193, Japan.ORCID 0000-0002-6129-8299
Rika SakaiDepartment of Oncology, Kanagawa Cancer Center, Kanagawa, Yokohama 241-8515, Japan.
Katsuyoshi TakataDepartment of Pathology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Tadashi YoshinoDepartment of Pathology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Silvia BeaDepartment of Pathology, Hospital Clinic Barcelona, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), University of Barcelona, Rossello 149-153, 08036 Barcelona, Spain.ORCID 0000-0001-7192-2385
Elias CampoDepartment of Pathology, Hospital Clinic Barcelona, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), University of Barcelona, Rossello 149-153, 08036 Barcelona, Spain.
Edoardo MissiagliaInstitute of Pathology, Lausanne University Hospital, Lausanne University, Vaud, 1015 Lausanne, Switzerland.
Justine BouillyInstitute of Pathology, Lausanne University Hospital, Lausanne University, Vaud, 1015 Lausanne, Switzerland.
Audrey LetourneauInstitute of Pathology, Lausanne University Hospital, Lausanne University, Vaud, 1015 Lausanne, Switzerland.
Laurence de LevalInstitute of Pathology, Lausanne University Hospital, Lausanne University, Vaud, 1015 Lausanne, Switzerland.
Naoya NakamuraDepartment of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Kanagawa, Isehara 259-1193, Japan.
Tokai University · JPUniversity of Lausanne · CHCentro de Investigación Biomédica en Red de Cáncer · ESOkayama University · JPKanagawa Prefectural Hospital Organization · JP

Funding

Ministry of Education, Culture, Sports, Science and Technology (MEXT) and the Japan Society for the Promotion of Science (JSPS) KAKENHI grants 18K15101 and 25860278
6 · The paper itself

Abstract

Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is a rare primary T-cell lymphoma of the digestive tract derived from intraepithelial lymphocytes and characterized by an aggressive clinical course. In this study, nine cases of Japanese MEITL were analyzed by targeted Next Generation Sequencing (NGS) and immunohistochemistry and were integrated with previously reported whole-genome copy number microarray-based assay data. The highlight of our findings is that all cases showed alterations of the tumor suppressor gene

Indexed as

copy-number changesgenome profileJAK/STAT pathwayMEITLmutational landscapeNGSSETD2

Identifiers

PMID33260897
PMCPMC7759862
OpenAlexW3106809242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.