Evidence map›Paper›PMID 33260892›Full record

ReviewCells2020

BRAF: A Two-Faced Janus.

Pasquale Pisapia, Francesco Pepe, Antonino Iaccarino, Roberta Sgariglia, Mariantonia Nacchio, Gianluca Russo, Gianluca Gragnano, Umberto Malapelle, Giancarlo Troncone

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. EnhancingQuantitative imaging in medicine and surgery · 2026
    Article
  4. Next-generation sequencing using a targeted gene panel in advanced solid tumors: five years of experience from an Italian referral institution.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  5. Free Energy and Flexibility Analysis of Autoinhibited Human BRAF.Journal of chemical information and modeling · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Diffuse large B-cell lymphoma withClinical case reports · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. The Impact ofCancers · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Pasquale PisapiaDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-6429-0620
Francesco PepeDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Antonino IaccarinoDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Roberta SgarigliaDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Mariantonia NacchioDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Gianluca RussoDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-2698-9470
Gianluca GragnanoDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Umberto MalapelleDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-3211-9957
Giancarlo TronconeDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-1630-5805
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gain-of-function of V-Raf Murine Sarcoma Viral Oncogene Homolog B (

Indexed as

Biomarkers, TumorHumansMutationNeoplasmsProto-Oncogene Proteins B-rafSignal TransductionBiomarkers, TumorProto-Oncogene Proteins B-rafBRAFmolecular oncologypredictive molecular pathologyprognostic biomarker

Identifiers

PMID33260892
PMCPMC7760616
OpenAlexW3108084482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.