Evidence map›Paper›PMID 33260783›Full record

ReviewMolecules (Basel, Switzerland)2020

Neuroprotective Effects of Quercetin in Pediatric Neurological Diseases.

Lourdes Alvarez-Arellano, Marcela Salazar-García, Juan Carlos Corona

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
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  9. Magnetic UiO-66-NHACS omega · 2023
    Article
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  11. A Potential Role for Neuroinflammation in ADHD.Advances in experimental medicine and biology · 2023
    Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lourdes Alvarez-ArellanoCONACYT-Hospital Infantil de México Federico Gómez, Mexico City 06720, Mexico.ORCID 0000-0002-3469-1407
Marcela Salazar-GarcíaLaboratorio de Investigación en Biología del Desarrollo y Teratogénesis Experimental, Hospital Infantil de México Federico Gómez, Mexico City 06720, Mexico.
Juan Carlos CoronaLaboratory of Neurosciences, Hospital Infantil de México Federico Gómez, Mexico City 06720, Mexico.ORCID 0000-0003-4907-437X
Hospital Infantil de México Federico Gómez · MX

Funding

Fondos Federales HIM 2018/030 SSA 1497
6 · The paper itself

Abstract

Oxidative stress is a crucial event underlying several pediatric neurological diseases, such as the central nervous system (CNS) tumors, autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). Neuroprotective therapy with natural compounds used as antioxidants has the potential to delay, ameliorate or prevent several pediatric neurological diseases. The present review provides an overview of the most recent research outcomes following quercetin treatment for CNS tumors, ASD and ADHD as well as describes the potential in vitro and in vivo ameliorative effect on oxidative stress of bioactive natural compounds, which seems like a promising future therapy for these diseases. The neuroprotective effects of quercetin against oxidative stress can also be applied in the management of several neurodegenerative disorders with effects such as anti-cancer, anti-inflammatory, anti-viral, anti-obesity and anti-microbial. Therefore, quercetin appears to be a suitable adjuvant for therapy against pediatric neurological diseases.

Indexed as

ChildHumansNeurodegenerative DiseasesNeuroprotective AgentsQuercetinNeuroprotective AgentsQuercetinneuroprotectionoxidative stresspediatric diseasesquercetin

Identifiers

PMID33260783
PMCPMC7731313
OpenAlexW3110625572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.