Evidence map›Paper›PMID 33260762›Full record

ReviewAnimals : an open access journal from MDPI2020

Improvement of Disease Resistance in Livestock: Application of Immunogenomics and CRISPR/Cas9 Technology.

Md Aminul Islam, Sharmin Aqter Rony, Mohammad Bozlur Rahman, Mehmet Ulas Cinar, Julio Villena, Muhammad Jasim Uddin, Haruki Kitazawa

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 41 citations in OpenAlex.

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  7. Food science & nutrition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 6 countries.

Md Aminul IslamDepartment of Medicine, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.ORCID 0000-0003-1979-9652
Sharmin Aqter RonyDepartment of Parasitology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.ORCID 0000-0002-2754-0571
Mohammad Bozlur RahmanDepartment of Livestock Services, Krishi Khamar Sarak, Farmgate, Dhaka 1215, Bangladesh.
Mehmet Ulas CinarDepartment of Animal Science, Faculty of Agriculture, Erciyes University, 38039 Kayseri, Turkey.ORCID 0000-0001-5894-5072
Julio VillenaFood and Feed Immunology Group, Graduate School of Agricultural University Science, Tohoku University, Sendai 980-8572, Japan.ORCID 0000-0003-4941-4960
Muhammad Jasim UddinDepartment of Medicine, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.ORCID 0000-0002-6732-5534
Haruki KitazawaFood and Feed Immunology Group, Graduate School of Agricultural University Science, Tohoku University, Sendai 980-8572, Japan.ORCID 0000-0003-4586-5553
Tohoku University · JPBangladesh Agricultural University · BDBangladesh Livestock Research Institute · BDConsejo Nacional de Investigaciones Científicas y Técnicas · ARThe University of Queensland · AUWashington State University · US

Funding

ANPCyT-FONCyT Grant PICT-2016-0410Challenging Exploratory Research (23658216)Grant-in-Aid for Scientific Research (A) (19H00965), (B) (21380164, 24380146 and 16H05019)NARO Bio-oriented Technology Research Advancement Institution (research program on the development of innovative technology No.01002A
6 · The paper itself

Abstract

Disease occurrence adversely affects livestock production and animal welfare, and have an impact on both human health and public perception of food-animals production. Combined efforts from farmers, animal scientists, and veterinarians have been continuing to explore the effective disease control approaches for the production of safe animal-originated food. Implementing the immunogenomics, along with genome editing technology, has been considering as the key approach for safe food-animal production through the improvement of the host genetic resistance. Next-generation sequencing, as a cutting-edge technique, enables the production of high throughput transcriptomic and genomic profiles resulted from host-pathogen interactions. Immunogenomics combine the transcriptomic and genomic data that links to host resistance to disease, and predict the potential candidate genes and their genomic locations. Genome editing, which involves insertion, deletion, or modification of one or more genes in the DNA sequence, is advancing rapidly and may be poised to become a commercial reality faster than it has thought. The clustered regulatory interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) [CRISPR/Cas9] system has recently emerged as a powerful tool for genome editing in agricultural food production including livestock disease management. CRISPR/Cas9 mediated insertion of

Indexed as

bioinformaticsdisease resistancegenome editinglivestocknext generation sequencingtranscriptomics

Identifiers

PMID33260762
PMCPMC7761152
OpenAlexW3107986602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.