Evidence map›Paper›PMID 33260746›Full record

ReviewInternational journal of molecular sciences2020

Adipokines in the Skin and in Dermatological Diseases.

Dóra Kovács, Fruzsina Fazekas, Attila Oláh, Dániel Törőcsik

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05471388 (Assessment of Serum Asprosin Level in Male Patients With Acne Vulgaris), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05471388 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Assessment of Serum Asprosin Level in Male Patients With Acne Vulgaris

TypeinterventionalSponsorSohag UniversityRan2022 to 2023Enrolled72ConditionsAcne VulgarisArmsserum asprosin
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
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  13. Article
  14. Review
  15. Metformin Therapy for Acne Vulgaris: A Meta-Analysis.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. The Role of Adipokines in the Pathogenesis of Psoriasis.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dóra KovácsDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98., 4032 Debrecen, Hungary.ORCID 0000-0002-8300-3519
Fruzsina FazekasDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98., 4032 Debrecen, Hungary.
Attila OláhDepartment of Physiology, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98., 4032 Debrecen, Hungary.ORCID 0000-0003-4122-5639
Dániel TörőcsikDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98., 4032 Debrecen, Hungary.
University of Debrecen · HU

Funding

European Union and the European Regional Development Fund GINOP-2.3.2-15-2016-00005Hungarian National Research, Development and Innovation Fund FK-132296National Research, Development and Innovation Office 134235National Research, Development and Innovation Office EFOP-3.6.3-VEKOP-16-2017-00009New National Excellence Program of the Ministry of Human Capacities ÚNKP-20-5-DE-41
6 · The paper itself

Abstract

Adipokines are the primary mediators of adipose tissue-induced and regulated systemic inflammatory diseases; however, recent findings revealed that serum levels of various adipokines correlate also with the onset and the severity of dermatological diseases. Importantly, further data confirmed that the skin serves not only as a target for adipokine signaling, but may serve as a source too. In this review, we aim to provide a complex overview on how adipokines may integrate into the (patho) physiological conditions of the skin by introducing the cell types, such as keratinocytes, fibroblasts, and sebocytes, which are known to produce adipokines as well as the signals that target them. Moreover, we discuss data from in vivo and in vitro murine and human studies as well as genetic data on how adipokines may contribute to various aspects of the homeostasis of the skin, e.g., melanogenesis, hair growth, or wound healing, just as to the pathogenesis of dermatological diseases such as psoriasis, atopic dermatitis, acne, rosacea, and melanoma.

Indexed as

AdipokinesAnimalsHumansSkinSkin DiseasesWound HealingAdipokinesacneadipokinesatopic dermatitisfibroblastshair growthkeratinocytesmelanocytesmelanomapsoriasissebocytes

Identifiers

PMID33260746
PMCPMC7730960
OpenAlexW3106632815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.