Evidence map›Paper›PMID 33260709›Full record

ArticleJournal of clinical medicine2020

Elastography of Endometrium in Women Taking Tamoxifen: A New Approach to an Old Diagnostic Problem.

Krzysztof Jabłoński, Łukasz Kurek, Maciej Żukowski, Natalia Data-Jabłońska, Karolina Żukowska, Anna J Milewska, Aleksandra Lipka, Marcin Jóźwik

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Krzysztof JabłońskiClinic of Gynecology, Oncological Gynecology and Obstetrics, Municipal Polyclinical Hospital in Olsztyn, Niepodległości Str. 44, 10-045 Olsztyn, Poland.
Łukasz KurekClinic of Gynecology, Oncological Gynecology and Obstetrics, Municipal Polyclinical Hospital in Olsztyn, Niepodległości Str. 44, 10-045 Olsztyn, Poland.
Maciej ŻukowskiClinic of Gynecology, Oncological Gynecology and Obstetrics, Municipal Polyclinical Hospital in Olsztyn, Niepodległości Str. 44, 10-045 Olsztyn, Poland.
Natalia Data-JabłońskaClinic of Gynecology, Oncological Gynecology and Obstetrics, Municipal Polyclinical Hospital in Olsztyn, Niepodległości Str. 44, 10-045 Olsztyn, Poland.
Karolina ŻukowskaDepartment of Oncology and Immunooncology, Hospital Ministry of the Interior and Administration with Warmia and Mazury Oncology Center, Olsztyn, Wojska Polskiego Ave. 37, 10-228 Olsztyn, Poland.
Anna J MilewskaDepartment of Statistics and Medical Informatics, Medical University of Białystok, Białystok, Szpitalna Str. 37, 15-295 Białystok, Poland.
Aleksandra LipkaDepartment of Gynecology and Obstetrics, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Żołnierska Str 18, 10-561 Olsztyn, Poland.ORCID 0000-0003-0815-6635
Marcin JóźwikClinic of Gynecology, Oncological Gynecology and Obstetrics, Municipal Polyclinical Hospital in Olsztyn, Niepodległości Str. 44, 10-045 Olsztyn, Poland.ORCID 0000-0003-3401-2758
University of Warmia and Mazury in Olsztyn · PLMedical University of Białystok · PL

Funding

Uniwersytet Warmińsko-Mazurski w Olsztynie 61.610.001-110
6 · The paper itself

Abstract

Tamoxifen is a commonly used selective estrogen receptor modulator applied in the treatment for breast cancer. However, in the endometrium, Tamoxifen stimulates tissue growth, cellular transformation, the migration of the cells, and metastatic potential in endometrial cancer. Considering that uterine cancer is the most common neoplasm of the reproductive tract and the third most common neoplastic disease in women, the aim of this study was to investigate if applying elastography in examining the endometrium was beneficial for uterine cancer screening protocols in women on selective estrogen receptor modulator therapy. This study was based on the execution of a classic assessment of the endometrium that included the evaluation of the following: echogenicity, central endometrial stripe, presence of fluid in the uterine lumen, myometrium-endometrium interface, intensity of vascularization and vascular pattern. An ultrasound presentation was then processed and analyzed with elastography. The values of the elastography parameters demonstrated good consistency for the measurement of the softest endometrial layer thickness in elastography. A strong positive correlation (R = 0.56) was demonstrated between the endometrial thickness, as determined by ultrasound examination, and the softest endometrial layer in elastography (

Indexed as

elastographyendometrial cancerendometrial cancer screeningendometriumSERM therapytamoxifenthe softest endometrium layerultrasonography

Identifiers

PMID33260709
PMCPMC7760647
OpenAlexW3108112249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.