Evidence map›Paper›PMID 33260650›Full record

ArticleGenes2020

Comprehensive Transcriptomic Analysis Identifies

Jung-Yu Kan, Sin-Hua Moi, Wen-Chun Hung, Ming-Feng Hou, Fang-Ming Chen, Shen-Liang Shih, Jun-Ping Shiau, Chung-Liang Li, Chih-Po Chiang

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  3. Tumor-expressed GPNMB orchestrates Siglec-9Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jung-Yu KanDepartment of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Sin-Hua MoiCenter of Cancer Program Development, E-Da Cancer Hospital, I-Shou University, Kaohsiung 82445, Taiwan.ORCID 0000-0002-4082-1909
Wen-Chun HungNational Institute of Cancer Research, National Health Research Institutes, Tainan 70456, Taiwan.
Ming-Feng HouDepartment of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0001-6030-9702
Fang-Ming ChenDepartment of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Shen-Liang ShihDepartment of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0001-8488-5931
Jun-Ping ShiauDepartment of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Chung-Liang LiDepartment of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Chih-Po ChiangDepartment of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0002-5399-3902
Kaohsiung Medical University · TWI-Shou University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypersialylation caused by the overexpression of sialyltransferases (STs) is a common feature in cancer that is associated with several characteristics of tumorigenesis. Thus, identifying cancer-associated STs is critical for cancer therapy. However, ST screening has been frequently conducted in cell line models. In this study, we conducted a comprehensive analysis of STs in the clinical database and identified the STs related with the survival of breast cancer patients. RNA sequencing (RNA-Seq) data of 496 patients were obtained from The Cancer Genome Atlas Breast Invasive Carcinoma (TCGA-BRCA). Of the eight mapped STs,

Indexed as

Breast NeoplasmsDatabases, Nucleic AcidNeoplasm ProteinsSialyltransferasesAgedDisease-Free SurvivalFemaleGene Expression ProfilingHumansMiddle AgedSurvival Ratealpha-N-acetylneuraminate alpha-2,8-sialyltransferaseNeoplasm ProteinsSialyltransferasesbreast cancerhypersialylationRNA sequencingsialic acidsialyltransferaseST8SIA1

Identifiers

PMID33260650
PMCPMC7760851
OpenAlexW3110279575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.