Evidence map›Paper›PMID 33260597›Full record

ArticleNutrients2020

Nutrition Support in Liver Transplantation and Postoperative Recovery: The Effects of Vitamin D Level and Vitamin D Supplementation in Liver Transplantation.

Junshi Doi, Amika Moro, Masato Fujiki, Bijan Eghtesad, Cristiano Quintini, K V Narayanan Menon, Koji Hashimoto, Kazunari Sasaki

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Post-Transplant Vitamin D Deficiency in Lung Transplant Recipients: Impact on Outcomes and Prognosis.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Observational
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Junshi DoiDepartment of General Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0001-7113-4864
Amika MoroDepartment of General Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Masato FujikiDepartment of General Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-1118-0081
Bijan EghtesadDepartment of General Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-7857-0092
Cristiano QuintiniDepartment of General Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
K V Narayanan MenonDepartment of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH 44195, USA.
Koji HashimotoDepartment of General Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Kazunari SasakiDepartment of General Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D plays an important role in the arena of liver transplantation. In addition to affecting skeletal health significantly, it also clinically exerts immune-modulatory properties. Vitamin D deficiency is one of the nutritional issues in the perioperative period of liver transplantation (LT). Although vitamin D deficiency is known to contribute to higher incidences of acute cellular rejection (ACR) and graft failure in other solid organ transplantation, such as kidneys and lungs, its role in LT is not well understood. The aim of this study was to investigate the clinical implication of vitamin D deficiency in LT. LT outcomes were reviewed in a retrospective cohort of 528 recipients during 2014-2019. In the pre-transplant period, 55% of patients were vitamin-D-deficient. The serum vitamin D level was correlated with the model for end-stage liver disease (MELD-Na) score. Vitamin D deficiency in the post-transplant period was associated with lower survival after LT, and the post-transplant supplementation of vitamin D was associated with a lower risk of ACR. The optimal vitamin D status and vitamin D supplementation in the post-transplant period may prolong survival and reduce ACR incidence.

Indexed as

Liver TransplantationNutritional SupportTransplant RecipientsFemaleHumansLiver CirrhosisMaleMiddle AgedVitamin DVitamin D DeficiencyVitamin Dliver transplantrejectionsurvivalvitamin Dvitamin D supplementation

Identifiers

PMID33260597
PMCPMC7759902
OpenAlexW3109467927

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.