Evidence map›Paper›PMID 33260473›Full record

ArticlePolymers2020

Chemical Hydrogels Bearing Thiazolium Groups with a Broad Spectrum of Antimicrobial Behavior.

Alexandra Muñoz-Bonilla, Jakub Zagora, Daniela Plachá, Coro Echeverría, Alberto Chiloeches, Marta Fernández-García

Abstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandra Muñoz-BonillaInstituto de Ciencia y Tecnología de Polímeros (ICTP-CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0003-0210-1246
Jakub ZagoraNanotechnology Centre, VŠB-Technical University of Ostrava, 15. Listopadu 2172/15, 70800 Ostrava-Poruba, Czech Republic.
Daniela PlacháNanotechnology Centre, VŠB-Technical University of Ostrava, 15. Listopadu 2172/15, 70800 Ostrava-Poruba, Czech Republic.ORCID 0000-0001-7108-0739
Coro EcheverríaInstituto de Ciencia y Tecnología de Polímeros (ICTP-CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.
Alberto ChiloechesInstituto de Ciencia y Tecnología de Polímeros (ICTP-CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.
Marta Fernández-GarcíaInstituto de Ciencia y Tecnología de Polímeros (ICTP-CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0003-2061-0351

Funding

Consejo Superior de Investigaciones Científicas i-LINK4911Ministerio de Ciencia, Innovación y Universidades MAT2016-78437-RMinisterstvo Školství, Mládeže a Tělovýchovy CZ.02.1.01/0.0/0.0/17\_049/0008441Ministerstvo Školství, Mládeže a Tělovýchovy SP2020/70
6 · The paper itself

Abstract

Several hydrogels based on 2-hydroxyethyl methacrylate and a methacrylic monomer containing a thiazole group in its lateral chain have been prepared by thermal polymerization at 60 °C in water solution varying the chemical composition of the gels. The posterior quaternization of the thiazole groups with methyl iodine has rendered positively charged hydrogels with potential antimicrobial activity. This modification has been structurally characterized by infrared spectroscopy, whereas the thermal stability of all hydrogels has been studied by thermal degradation in inert atmosphere. The swelling behavior in distilled water and the rheology of the different hydrogels have been analyzed as a function of 2-(4-methylthiazol-5-yl)ethyl methacrylate (MTA) monomer content as well as its methylation. Finally, the active character of hydrogels against Gram-positive and Gram-negative bacteria and fungi has been evaluated, revealing excellent antimicrobial activity against all tested microorganisms. The methylated hydrogels could be used as potential materials for wound healing or contact lens applications.

Indexed as

antimicrobialhydrogelquaternizationthiazole

Identifiers

PMID33260473
PMCPMC7761506

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.