Evidence map›Paper›PMID 33260400›Full record

ArticleMarine drugs2020

A New Bioassay Platform Design for the Discovery of Small Molecules with Anticancer Immunotherapeutic Activity.

Carmela Gallo, Giusi Barra, Marisa Saponaro, Emiliano Manzo, Laura Fioretto, Marcello Ziaco, Genoveffa Nuzzo, Giuliana d'Ippolito, Raffaele De Palma, Angelo Fontana

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
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  4. Bioactive Polyketides fromMarine drugs · 2025
    Review
  5. Antidiabetic potential of vanadium complexes combined with olive leaf extracts: a viable approach to reduce metal toxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Carmela GalloBio-Organic Chemistry Unit, CNR-Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Naples, Italy.ORCID 0000-0002-1665-2615
Giusi BarraBio-Organic Chemistry Unit, CNR-Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Naples, Italy.ORCID 0000-0003-2395-6710
Marisa SaponaroBio-Organic Chemistry Unit, CNR-Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Naples, Italy.
Emiliano ManzoBio-Organic Chemistry Unit, CNR-Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Naples, Italy.ORCID 0000-0002-7394-020X
Laura FiorettoConsorzio Italbiotec, Via Fantoli, 16/15, 20138 Milan, Italy.
Marcello ZiacoBioSearch Srl., Villa Comunale c/o Stazione Zoologica "A.Dohrn", 80121 Naples, Italy.
Genoveffa NuzzoBio-Organic Chemistry Unit, CNR-Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Naples, Italy.ORCID 0000-0001-7065-2379
Giuliana d'IppolitoBio-Organic Chemistry Unit, CNR-Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Naples, Italy.
Raffaele De PalmaBio-Organic Chemistry Unit, CNR-Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Naples, Italy.
Angelo FontanaBio-Organic Chemistry Unit, CNR-Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Naples, Italy.ORCID 0000-0002-5453-461X
Ospedale Policlinico San Martino · ITStazione Zoologica Anton Dohrn · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy takes advantage of the immune system to prevent, control, and eliminate neoplastic cells. The research in the field has already led to major breakthroughs to treat cancer. In this work, we describe a platform that integrates

Indexed as

Biological AssayDrug DiscoveryImmunotherapyAnimalsAntineoplastic AgentsCell Line, TumorCytotoxicity, ImmunologicDendritic CellsHigh-Throughput Screening AssaysImmunity, InnateLymphocyte ActivationMiceNeoplasmsPhenotypeSmall Molecule LibrariesT-LymphocytesAntineoplastic AgentsSmall Molecule Librariesanticancerbioassay platformchemical immunologydendritic celldrug discoveryhigh throughputimmunotherapyscreening guidelines

Identifiers

PMID33260400
PMCPMC7760914
OpenAlexW3108639995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.