Evidence map›Paper›PMID 33260363›Full record

ArticleCancers2020

Image-Guided Multisession Radiosurgery of Skull Base Meningiomas.

Alfredo Conti, Antonio Pontoriero, Giuseppe Iatì, Salvatore M Cardali, Anna Brogna, Filippo Friso, Vittoria Rosetti, Matteo Zoli, Silvana Parisi, Alberto Cacciola and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Alfredo ContiUnit of Neurosurgery, IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139 Bologna, Italy.
Antonio PontorieroDepartment of Radiation Oncology, BIOMORF, University of Messina, via Consolare Valeria 1, 98122 Messina, Italy.
Giuseppe IatìDepartment of Radiation Oncology, BIOMORF, University of Messina, via Consolare Valeria 1, 98122 Messina, Italy.
Salvatore M CardaliDepartment of Neurosurgery, BIOMORF, University of Messina, via Consolare Valeria 1, 98122 Messina, Italy.
Anna BrognaDepartment of Radiation Oncology, BIOMORF, University of Messina, via Consolare Valeria 1, 98122 Messina, Italy.
Filippo FrisoDipartimento di Scienze Biomediche e Neuromotorie (DIBINEM), Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.ORCID 0000-0003-1333-9882
Vittoria RosettiDipartimento di Scienze Biomediche e Neuromotorie (DIBINEM), Alma Mater Studiorum University of Bologna, 40126 Bologna, Italy.
Matteo ZoliUnit of Neurosurgery, IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139 Bologna, Italy.ORCID 0000-0001-8838-5408
Silvana ParisiDepartment of Radiation Oncology, BIOMORF, University of Messina, via Consolare Valeria 1, 98122 Messina, Italy.ORCID 0000-0001-9135-1639
Alberto CacciolaDepartment of Radiation Oncology, BIOMORF, University of Messina, via Consolare Valeria 1, 98122 Messina, Italy.ORCID 0000-0001-9412-4116
Sara LilloDepartment of Radiation Oncology, BIOMORF, University of Messina, via Consolare Valeria 1, 98122 Messina, Italy.
Stefano PergolizziDepartment of Radiation Oncology, BIOMORF, University of Messina, via Consolare Valeria 1, 98122 Messina, Italy.
Diego MazzatentaUnit of Neurosurgery, IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139 Bologna, Italy.
University of Messina · ITIstituto delle Scienze Neurologiche di Bologna · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe efficacy of single-session stereotactic radiosurgery (sSRS) for the treatment of intracranial meningioma is widely recognized. However, sSRS is not always feasible in cases of large tumors and those lying close to critically radiation-sensitive structures. When surgery is not recommended, multi-session stereotactic radiosurgery (mSRS) can be applied. Even so, the efficacy and best treatment schedule of mSRS are not yet established. The aim of this study is to validate the role of mSRS in the treatment of skull base meningiomas.

methodsA retrospective analysis of patients with skull base meningiomas treated with mSRS (two to five fractions) at the University of Messina, Italy, from 2008 to 2018, was conducted.

results156 patients met the inclusion criteria. The median follow-up period was 36.2 ± 29.3 months. Progression-free survival at 2-, 5-, and 10- years was 95%, 90%, and 80.8%, respectively. There were no new visual or motor deficits, nor cranial nerves impairments, excluding trigeminal neuralgia, which was reported by 5.7% of patients. One patient reported carotid occlusion and one developed brain edema.

conclusionMultisession radiosurgery is an effective approach for skull base meningiomas. The long-term control is comparable to that obtained with conventionally-fractionated radiotherapy, while the toxicity rate is very limited.

Indexed as

CyberKnifehypofractionated stereotactic radiotherapyimage-guided radiotherapymeningiomaradiosurgeryskull base

Identifiers

PMID33260363
PMCPMC7761100
OpenAlexW3109055597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.