Evidence map›Paper›PMID 33260299›Full record

ArticleMarine drugs2020

Synthesis, Cytotoxic Activity Evaluation and Quantitative Structure-Activity Analysis of Substituted 5,8-Dihydroxy-1,4-Naphthoquinones and their

Sergey Polonik, Galina Likhatskaya, Yuri Sabutski, Dmitry Pelageev, Vladimir Denisenko, Evgeny Pislyagin, Ekaterina Chingizova, Ekaterina Menchinskaya, Dmitry Aminin

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Neuroprotective Effect of 1,4-Naphthoquinones in anInternational journal of molecular sciences · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sergey PolonikG.B. Elyakov Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of Russian Academy of Sciences, Prospekt 100-let Vladivostoku, 159, 690022 Vladivostok, Russia.
Galina LikhatskayaG.B. Elyakov Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of Russian Academy of Sciences, Prospekt 100-let Vladivostoku, 159, 690022 Vladivostok, Russia.ORCID 0000-0003-1937-1680
Yuri SabutskiG.B. Elyakov Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of Russian Academy of Sciences, Prospekt 100-let Vladivostoku, 159, 690022 Vladivostok, Russia.
Dmitry PelageevG.B. Elyakov Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of Russian Academy of Sciences, Prospekt 100-let Vladivostoku, 159, 690022 Vladivostok, Russia.ORCID 0000-0002-8793-7511
Vladimir DenisenkoG.B. Elyakov Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of Russian Academy of Sciences, Prospekt 100-let Vladivostoku, 159, 690022 Vladivostok, Russia.
Evgeny PislyaginG.B. Elyakov Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of Russian Academy of Sciences, Prospekt 100-let Vladivostoku, 159, 690022 Vladivostok, Russia.ORCID 0000-0002-3558-0821
Ekaterina ChingizovaG.B. Elyakov Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of Russian Academy of Sciences, Prospekt 100-let Vladivostoku, 159, 690022 Vladivostok, Russia.
Ekaterina MenchinskayaG.B. Elyakov Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of Russian Academy of Sciences, Prospekt 100-let Vladivostoku, 159, 690022 Vladivostok, Russia.
Dmitry AmininG.B. Elyakov Pacific Institute of Bioorganic Chemistry of Far Eastern Branch of Russian Academy of Sciences, Prospekt 100-let Vladivostoku, 159, 690022 Vladivostok, Russia.
Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences · RUFar Eastern Federal University · RUKaohsiung Medical University · TW

Funding

Russian Science Foundation 19-14-00047
6 · The paper itself

Abstract

Based on 6,7-substituted 2,5,8-trihydroxy-1,4-naphtoquinones (1,4-NQs) derived from sea urchins, five new acetyl-

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorCell SurvivalDose-Response Relationship, DrugGlycosidesInhibitory Concentration 50MiceMolecular StructureNaphthoquinonesNeuroblastomaQuantitative Structure-Activity RelationshipSea UrchinsAntineoplastic AgentsGlycosidesnaphthazarinNaphthoquinones5,8-dihydroxy-1,4-naphthoquinonecytotoxic activityneuroblastoma Neuro-2a cellsO-glucosideQSARthiomethylglycoside

Identifiers

PMID33260299
PMCPMC7761386
OpenAlexW3108391715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.