Evidence map›Paper›PMID 33260195›Full record

ArticleNature2021

A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate.

Lorena Sanchez-Felipe, Thomas Vercruysse, Sapna Sharma, Ji Ma, Viktor Lemmens, Dominique Van Looveren, Mahadesh Prasad Arkalagud Javarappa, Robbert Boudewijns, Bert Malengier-Devlies, Laurens Liesenborghs and 38 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 1 synthesis or guideline pooled it, 187 citations in OpenAlex.

  1. Pooled it
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  6. CD4Nature immunology · 2026
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73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors at 7 institutions in 5 countries.

Lorena Sanchez-Felipe *KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-6928-0931
Thomas Vercruysse *KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-8649-777X
Sapna Sharma *KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-3493-252X
Ji Ma *KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-0912-2632
Viktor Lemmens *KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-2507-9029
Dominique Van Looveren *KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0001-6439-3753
Mahadesh Prasad Arkalagud Javarappa *KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-5792-6600
Robbert Boudewijns *KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.
Bert Malengier-Devlies *KU Leuven Department of Microbiology, Immunology and Transplantation,Rega Institute, Immunity and Inflammation Research Group, Immunobiology Unit, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-3527-1145
Laurens Liesenborghs *KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0001-5616-8548
Suzanne J F KapteinKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-7935-0219
Carolien De KeyzerKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.
Lindsey BervoetsKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.
Sarah DebaveyeKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-3969-1019
Madina RasulovaKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0001-9023-0800
Laura SeldeslachtsKU Leuven Department of Imaging and Pathology, Biomedical MRI and MoSAIC, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-9562-2923
Li-Hsin LiKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-2905-4745
Sander JansenKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-9344-131X
Michael Bright YakassKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-6903-0633
Babs E VerstrepenDepartment of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands.ORCID http://orcid.org/0000-0002-4666-0798
Kinga P BöszörményiDepartment of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands.ORCID http://orcid.org/0000-0001-5330-2617
Gwendoline Kiemenyi-KayereDepartment of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands.
Nikki van DrielAnimal Science Department, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands.ORCID http://orcid.org/0000-0003-3300-8204
Osbourne QuayeGlobal Virus Network (GVN), Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-0621-876X
Xin ZhangKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0001-8520-1060
Sebastiaan Ter HorstKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0001-7981-6376
Niraj MishraKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.
Ward DeboutteKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratorium Klinische en Epidemiologische Virologie, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-3829-1056
Jelle MatthijnssensKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratorium Klinische en Epidemiologische Virologie, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-1188-9733
Lotte CoelmontKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-7888-4534
Corinne VandermeulenLeuven University Vaccinology Center (LUVAC), KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-1954-7554
Elisabeth HeylenKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-4359-7225
Valentijn VergoteKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-4436-3212
Dominique ScholsKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.
Zhongde WangDepartment of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, USA.ORCID http://orcid.org/0000-0003-2441-4729
Willy BogersDepartment of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands.ORCID http://orcid.org/0000-0002-4563-8513
Thijs KuikenDepartment of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0001-5501-9049
Ernst VerschoorDepartment of Virology, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands.ORCID http://orcid.org/0000-0003-0912-2074
Christopher CawthorneKU Leuven Department of Imaging and Pathology, Nuclear Medicine and Molecular Imaging, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-5975-0354
Koen Van LaereKU Leuven Department of Imaging and Pathology, Nuclear Medicine and Molecular Imaging, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0001-5200-7245
Ghislain OpdenakkerKU Leuven Department of Microbiology, Immunology and Transplantation,Rega Institute, Immunity and Inflammation Research Group, Immunobiology Unit, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-1714-2294
Greetje Vande VeldeKU Leuven Department of Imaging and Pathology, Biomedical MRI and MoSAIC, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-5633-3993
Birgit WeynandKU Leuven Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0003-4246-6303
Dirk E TeuwenKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium.
Patrick MatthysKU Leuven Department of Microbiology, Immunology and Transplantation,Rega Institute, Immunity and Inflammation Research Group, Immunobiology Unit, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-9685-6836
Johan NeytsKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium. johan.neyts@kuleuven.be.ORCID http://orcid.org/0000-0002-0033-7514
Hendrik Jan ThibautKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium. hendrikjan.thibaut@kuleuven.be.ORCID http://orcid.org/0000-0001-5785-8276
Kai DallmeierKU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology and Chemotherapy, Molecular Vaccinology and Vaccine Discovery, KU Leuven, Leuven, Belgium. kai.dallmeier@kuleuven.be.ORCID http://orcid.org/0000-0002-8117-9166
Rega Institute for Medical Research · BEBiomedical Primate Research Centre · NLKU Leuven · BEUniversity of Ghana · GHDepartment of Public Health · USErasmus MC · NLUtah State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expanding pandemic of coronavirus disease 2019 (COVID-19) requires the development of safe, efficacious and fast-acting vaccines. Several vaccine platforms are being leveraged for a rapid emergency response

Indexed as

AnimalsCOVID-19COVID-19 VaccinesCricetinaeDisease Models, AnimalFemaleGenetic VectorsGlycosylationMacaca fascicularisMaleMesocricetusMiceSafetySARS-CoV-2Spike Glycoprotein, CoronavirusVaccines, AttenuatedCOVID-19 VaccinesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Vaccines, AttenuatedYellow Fever Vaccine

Identifiers

PMID33260195
OpenAlexW3109457440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.