Evidence map›Paper›PMID 33259817›Full record

ArticleActa tropica2021

Clinical and biochemical parameters of COVID-19 patients with prior or active dengue fever.

Isabella Márcia Soares Nogueira Teotônio, Juliana Lott de Carvalho, Luiz Cláudio Castro, Nadjar Nitz, Luciana Hagström, Geraldo Gonçalves Rios, Maria de Fátima Rodrigues de Oliveira, Bruno Stéfano Lima Dallago, Mariana Hecht

Open access · greenAbstract read
In one paragraph

Article in Acta tropica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Co-Infection between Dengue Virus and SARS-CoV-2 in Cali, Colombia.The American journal of tropical medicine and hygiene · 2023
    Article
  7. Dengue and COVID-19 Co-Circulation in the Peruvian Amazon: A Population-Based Study.The American journal of tropical medicine and hygiene · 2023
    Article
  8. Article
  9. Coinfection and cross-reaction of dengue and COVID-19: a case series analysis.Revista da Sociedade Brasileira de Medicina Tropical · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Viral coinfections in COVID-19.Journal of medical virology · 2021
    Review
  16. Observational
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Isabella Márcia Soares Nogueira TeotônioInterdisciplinary Laboratory of Biosciences, Faculty of Medicine, University of Brasília, Brasília, Brazil; Nucleus of clinical pathology of Planaltina Regional Hospital, DF.
Juliana Lott de CarvalhoInterdisciplinary Laboratory of Biosciences, Faculty of Medicine, University of Brasília, Brasília, Brazil; Genomic Sciences and Biotechnology Program, Catholic University of Brasília, Brasília, Brazil.
Luiz Cláudio CastroInterdisciplinary Laboratory of Biosciences, Faculty of Medicine, University of Brasília, Brasília, Brazil.
Nadjar NitzInterdisciplinary Laboratory of Biosciences, Faculty of Medicine, University of Brasília, Brasília, Brazil.
Luciana HagströmInterdisciplinary Laboratory of Biosciences, Faculty of Medicine, University of Brasília, Brasília, Brazil.
Geraldo Gonçalves RiosNucleus of clinical pathology of Planaltina Regional Hospital, DF.
Maria de Fátima Rodrigues de OliveiraBasic Health Unit 05 of Planaltina, DF.
Bruno Stéfano Lima DallagoLaboratory of Animal Welfare, Faculty of Agronomy and Veterinary Medicine, University of Brasília, Brasília, Brazil.
Mariana HechtInterdisciplinary Laboratory of Biosciences, Faculty of Medicine, University of Brasília, Brasília, Brazil. Electronic address: marianahecht@gmail.com.
Universidade de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Originated in Wuhan, China, the coronavirus 19 disease (COVID-19) has quickly spread worldwide, reaching countries that already faced other endemics and epidemics. In Brazil, such a concerning situation includes arboviruses, among which the dengue virus stands out. Here, we determined the rate of SARS-CoV-2/dengue virus co-infection in a total of 178 patients with COVID-19 symtoms admitted into a large public hospital of the Federal District of Brazil. Furthermore, we evaluated whether prior or active dengue virus infection influenced hematological, biochemical, and clinical parameters of such patients. One hundred and twelve (63%) individuals tested positive for COVID-19, of which 43 (38.4%) were co-infected with dengue virus, and 50 (44.6%) had antibodies indicative of previous dengue infection. Co-infected patients showed lower numbers of circulating lymphocytes and monocytes, higher glucose rates, and a worse pulmonary condition. Of note, prior infections with dengue virus did not influence clinical parameters, but active dengue fever resulted in higher hospitalization rate. In conclusion, amid the current complex epidemiological scenario in Brazil, our data support the notion that SARS-CoV-2 and dengue co-infection affects an important percentage of COVID-19 patients and leads to worse clinical parameters, requiring greater attention from health authorities.

Indexed as

AdultAlanine TransaminaseAntibodies, ViralAspartate AminotransferasesBlood GlucoseBrazilCoinfectionCOVID-19Creatine KinaseDengueFemaleHospitalizationHumansImmunoglobulin GL-Lactate DehydrogenaseLymphocyte CountAlanine TransaminaseAntibodies, ViralAspartate AminotransferasesBlood GlucoseCreatine KinaseImmunoglobulin GL-Lactate DehydrogenaseCo-infectionDengue feverSARS-CoV-2Syndemic

Identifiers

PMID33259817
PMCPMC7698682
OpenAlexW3109876281

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.