Evidence map›Paper›PMID 33259750›Full record

ArticleJournal of the Royal Society, Interface2020

Biomimetic six-axis robots replicate human cardiac papillary muscle motion: pioneering the next generation of biomechanical heart simulator technology.

Annabel M Imbrie-Moore, Matthew H Park, Michael J Paulsen, Mark Sellke, Rohun Kulkami, Hanjay Wang, Yuanjia Zhu, Justin M Farry, Alexandra T Bourdillon, Christine Callinan and 4 more

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Annabel M Imbrie-MooreDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Matthew H ParkDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Michael J PaulsenDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Mark SellkeDepartment of Mathematics, Stanford University, Stanford, CA, USA.
Rohun KulkamiDepartment of Mechanical Engineering, Stanford University, Stanford, CA, USA.
Hanjay WangDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Yuanjia ZhuDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Justin M FarryDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Alexandra T BourdillonDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Christine CallinanDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Haley J LucianDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Camille E HironakaDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Daniela DeschampsDepartment of Mechanical Engineering, Stanford University, Stanford, CA, USA.
Y Joseph WooDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.

Funding

ANGIOGENIC TISSUE ENGINEERING TO LIMIT POST-INFARCTION VENTRICULAR REMODELINGR01HL089315 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WOO, Y JOSEPH · 2008 to 2023
$6.4M
Biomechanical Optimization of Mitral Valve Repair OperationsR01HL152155 · NHLBI · STANFORD UNIVERSITY · PI WOO, Y JOSEPH · 2020 to 2025
$5.9M
NHLBI NIH HHS R01 HL089315NHLBI NIH HHS R01 HL152155
6 · The paper itself

Abstract

Papillary muscles serve as attachment points for chordae tendineae which anchor and position mitral valve leaflets for proper coaptation. As the ventricle contracts, the papillary muscles translate and rotate, impacting chordae and leaflet kinematics; this motion can be significantly affected in a diseased heart. In

Indexed as

Mitral Valve InsufficiencyRoboticsBiomimeticsChordae TendineaeHumansPapillary Musclesbiomechanicscardiac imagingex vivo modellingrobotics

Identifiers

PMID33259750
PMCPMC7811588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.