Evidence map›Paper›PMID 33259745›Full record

ReviewOpen biology2020

Bronchoconstriction: a potential missing link in airway remodelling.

Michael J O'Sullivan, Thien-Khoi N Phung, Jin-Ah Park

Open access · goldAbstract readReview
In one paragraph

Review in Open biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Cough-Variant Asthma: A Review of Clinical Characteristics, Diagnosis, and Pathophysiology.The journal of allergy and clinical immunology. In practice · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael J O'SullivanDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Ave, Boston, MA, USA.
Thien-Khoi N PhungDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Ave, Boston, MA, USA.
Jin-Ah ParkDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Ave, Boston, MA, USA.
Harvard University · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Training Program in Molecular and Integrative Physiological SciencesT32HL007118 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LU, QUAN · 1985 to 2025
$14.3M
Physics of bronchial epithelial unjammingR01HL148152 · NHLBI · HARVARD SCHOOL OF PUBLIC HEALTH · PI FREDBERG, JEFFREY J, PARK, JIN-AH · 2019 to 2022
$2.2M
NHLBI NIH HHS R01 HL148152NHLBI NIH HHS T32 HL007118NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

In asthma, progressive structural changes of the airway wall are collectively termed airway remodelling. Despite its deleterious effect on lung function, airway remodelling is incompletely understood. As one of the important causes leading to airway remodelling, here we discuss the significance of mechanical forces that are produced in the narrowed airway during asthma exacerbation, as a driving force of airway remodelling. We cover

Indexed as

Airway RemodelingBronchoconstrictionAnimalsBiomarkersDisease ManagementDisease ProgressionDisease SusceptibilityHumansRespiratory MucosaSignal TransductionStress, MechanicalStress, PhysiologicalBiomarkersairway remodellingasthmabronchoconstrictionmechanical stress

Identifiers

PMID33259745
PMCPMC7776576
OpenAlexW3110441494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.