ArticlePloS one2020
Retinal vascular metrics difference by comparison of two image acquisition modes using a novel OCT angiography prototype.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
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- Geometric Decomposition of OCT Angiography in RVO: Unmasking Congestive Versus Compensatory Phenotypes and Deep Retina-Choroid Coupling.Translational vision science & technology · 2026Article
- Photoreceptor damage in pachychoroid pigment epitheliopathy.Eye (London, England) · 2025Article
- Comparison of a Scheimpflug Camera and Optical Coherence Tomography in Evaluating Keratoconic Eyes Post Keratoplasty.Journal of clinical medicine · 2025Article
- Retinal capillary density among healthy Egyptian and South Asian students: an optical coherence tomography angiography study.International journal of ophthalmology · 2025Article
- Choriocapillaris in Age-Related Macular Degeneration.Turkish journal of ophthalmology · 2024Review
- Qualitative and quantitative comparison of two semi-manual retinal vascular density analyzing methods on optical coherence tomography angiography images of healthy individuals.Scientific reports · 2023Article
- Progression Biomarkers of Microvascular and Photoreceptor Changes Upon Long-Term Evaluation in Type 1 Diabetes.Investigative ophthalmology & visual science · 2023Article
- Impact of Intravitreal Anti-VEGF Therapy on Microperimetry of the Retinal Nonperfusion Areas of Patients with Proliferative Diabetic Retinopathy.Ophthalmology and therapy · 2022Article
- Evaluation of macular microvascular density using optical coherence tomography angiography in patients with Posner-Schlossman syndrome.BMC ophthalmology · 2022Observational
- Towards standardizing retinal optical coherence tomography angiography: a review.Light, science & applications · 2022Review
- Cortisol awake response imbalance as an indicator of acute central serous chorioretinopathy: Relationship with choriocapillaris and choroidal features.Frontiers in medicine · 2022Article
- Analysis of Optic Nerve in Adults With Amblyopia Using OCTA.Frontiers in medicine · 2022Article
- Relationship of Choroidal Vasculature and Choriocapillaris Flow With Alterations of Salivary α-Amylase Patterns in Central Serous Chorioretinopathy.Investigative ophthalmology & visual science · 2021Article
- Choriocapillaris Vascular Density Changes: Healthy vs. Advanced Exudative Age-Related Macular Degeneration Previously Treated with Multiple Anti-VEGF Intravitreal Injections.Diagnostics (Basel, Switzerland) · 2021Article
- OCTAVA: An open-source toolbox for quantitative analysis of optical coherence tomography angiography images.PloS one · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the different impact of two enface OCTA image simultaneously acquired by means of a new prototype of Spectral-Domain Optical Coherence Tomography Angiography (SD-OCTA) on quantitative retinal vascular metrics.
methodsIn this prospective observational cross-sectional study 28 healthy subjects were enrolled. Macular (3x3 mm) OCTA images were acquired for all participants using Solix Fullrange OCT (Optovue Inc, Freemont CA, USA). The main outcome measurements were: Perfusion density (PD), vessel length density (VLD), and vessel diameter index (VDI) of both superficial capillary plexus (SCP) and deep capillary plexus (DCP), and choriocapillaris (CC) total flow-deficits area. Quantitative retinal vascular metrics were measured on binarized and skeletonized OCTA images by comparing not averaged and fast automated multiple averaged en face OCTA images.
resultsIn both SCP and DCP, PD significantly increased (p = 0,005 and p = 0,030, respectively), and VLD significantly decreased (p<0,001 and p = 0,004, respectively), and VDI increased (p<0,001 and p = 0,068, respectively), and total CC flow deficits area significantly decreased (p<0,001) by averaging multiple OCTA images.
conclusionsIn this study, we found a significant difference of quantitative retinal metrics by comparing two different image acquisition modes using a novel and fully automated averaging OCTA system in young healthy subjects.
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