ArticlePloS one2020
Metabolomics characterizes the metabolic changes of Lonicerae Japonicae Flos under different salt stresses.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 29 citations in OpenAlex.
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- Salt-Induced Changes in the Phenolic Content of Melon F2 Offspring Sprouts Obtained from Fruit Deseeding.Foods (Basel, Switzerland) · 2025Article
- Characterization and differential expression of DNA methyltransferase and demethylase genes in response to abiotic stress in Isodon rubescens.BMC plant biology · 2025Article
- Effects of exogenous Uniconazole (S3307) on oxidative damage and carbon metabolism of rice under salt stress.BMC plant biology · 2025Article
- Genome-wide identification, characterization, and expression analysis of the SOS1 gene family in the medicinal plantFrontiers in plant science · 2025Article
- Metabolomics reveals the response of hydroprimed maize to mitigate the impact of soil salinization.Frontiers in plant science · 2023Article
- Evaluation of metabolites in Iranian Licorice accessions under salinity stress and Azotobacter sp. inoculation.Scientific reports · 2022Article
- Lonicerae Japonicae Flos Attenuates Neutrophilic Inflammation by Inhibiting Oxidative Stress.Antioxidants (Basel, Switzerland) · 2022Article
- Review
- Article
- Salinity Stress Alters the Secondary Metabolic Profile ofInternational journal of molecular sciences · 2021Article
- Polysaccharides and polyphenol in driedPeerJ · 2021Article
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Authors and funding
12 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Salt stress affects the metabolic homeostasis of medicinal plants. However, medicinal plants are sessile organisms that cannot escape from salt stress. They acclimatize themselves to the stress by reprogramming their metabolic pathways. Lonicerae Japonicae Flos (LJF) with strong antioxidant activity is commonly used in traditional Chinese medicine, tea, and beverage. Nevertheless, the variation of integrated metabolites in LJF under different salt stresses remains unclear. In this study, High Performance Liquid Chromatography tandem triple time-of-flight mass spectrometry (HPLC- triple TOF-MS/MS) coupled with multivariate statistical analysis was applied to comparatively investigate the metabolites changes in LJF under different salt stress (0, 100, 200, 300 mM NaCl). Total 47 differential metabolites were screened from 79 metabolites identified in LJF under different salt stress. Low salt-treated group (100 mM NaCl) appeared to be the best group in terms of relative contents (peak areas) of the wide variety in bioactive components. Additionally, the phenylpropanoid pathway, monoterpenoid biosynthesis, glycolysis, TCA cycle, and alkaloid biosynthesis were disturbed in all salt-stress LJF. The results showed that LJF metabolisms were dramatically induced under salt stress and the quality of LJF was better under low salt stress. The study provides novel insights into the quality assessment of LJF under salt stress and a beneficial framework of knowledge applied to improvement the medicinal value of LJF.
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