Evidence map›Paper›PMID 33259019›Full record

ArticleSurgical endoscopy2021

Endoscopic vacuum therapy for in- and outpatient treatment of colorectal defects.

Florian Kühn, Ulrich Wirth, Julia Zimmermann, Nicola Beger, Sandro M Hasenhütl, Moritz Drefs, Christian Heiliger, Maria Burian, Jens Werner, Tobias S Schiergens

Open access · hybridAbstract read
In one paragraph

Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Dehiscence of colorectal anastomosis treated with noninvasive procedures.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Endoscopic Vacuum Therapy: When and How to Use It?GE Portuguese journal of gastroenterology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Florian KühnDepartment of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Hospital, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Ulrich WirthDepartment of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Hospital, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Julia ZimmermannDepartment of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Hospital, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Nicola BegerDepartment of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Hospital, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Sandro M HasenhütlDepartment of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Hospital, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Moritz DrefsDepartment of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Hospital, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Christian HeiligerDepartment of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Hospital, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Maria BurianDepartment of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Hospital, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Jens WernerDepartment of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Hospital, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany.
Tobias S SchiergensDepartment of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Hospital, Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany. tobias.schiergens@med.lmu.de.
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence for endoscopic vacuum therapy (EVT) for colorectal defects is still based on small patient series from various institutions, employing different treatment algorithms and methods. As EVT was invented at our institution 20 years ago, the aim was to report the efficacy and safety of EVT for colorectal defects as well as to analyze factors associated with efficacy, therapy duration, and outpatient treatment.

methodsCohort study with analysis of prospectively collected data of patients receiving EVT for colorectal defects at a tertiary referral center in Germany (n = 281).

resultsThe majority of patients had malignant disease (83%) and an American Society of Anesthesiologists classification of III/IV (81%). Most frequent indications for EVT were anastomotic leakage after sigmoid or rectal resection (67%) followed by rectal stump leakage (20%). EVT was successful in 256 out of 281 patients (91%). EVT following multi-visceral resection (P = 0.037) and recent surgical revision after primary surgery (P = 0.009) were risk factors for EVT failure. EVT-associated adverse events occurred in 27 patients (10%). Median treatment duration was 25 days. Previous chemo-radiation (P = 0.006) was associated with a significant longer duration of EVT. Outpatient treatment was conducted in 49% of patients with a median hospital stay reduction of 15 days and 98% treatment success. Younger patient age (P = 0.044) was associated with the possibility of outpatient treatment. Restoration of intestinal continuity was achieved in 60% of patients where technically possible with a 12-month rate of 52%.

conclusionsIn patients with colorectal defects, EVT appears to be a safe and effective, minimally invasive option for in- and outpatient treatment.

Indexed as

Colorectal NeoplasmsNegative-Pressure Wound TherapyAnastomotic LeakCohort StudiesHumansOutpatientsAnastomotic leakageColorectal defectsComplication managementEndoscopic vacuum therapyOutpatient treatment

Identifiers

PMID33259019
PMCPMC8599392
OpenAlexW3109919496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.