Evidence map›Paper›PMID 33258940›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020

Typhoid and Paratyphoid Cost of Illness in Bangladesh: Patient and Health Facility Costs From the Surveillance for Enteric Fever in Asia Project II.

Nelly Mejia, Sarah W Pallas, Samir Saha, Jamal Udin, K M Ishtiaque Sayeed, Denise O Garrett, Kashmira Date, Taiwo Abimbola

Abstract readCase Reports
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Typhoid fever.Nature reviews. Disease primers · 2023
    Review
  8. Article
  9. Article
  10. Typhoid in Bangladesh: Challenges, efforts, and recommendations.Annals of medicine and surgery (2012) · 2022
    Article
  11. Article
  12. Article
  13. Cost of Illness Due to Severe Enteric Fever in India.The Journal of infectious diseases · 2021
    Article
  14. Typhoid and Paratyphoid Cost of Illness in Nepal: Patient and Health Facility Costs From the Surveillance for Enteric Fever in Asia Project II.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  15. Typhoid and Paratyphoid Cost of Illness in Pakistan: Patient and Health Facility Costs From the Surveillance for Enteric Fever in Asia Project II.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  16. Introducing Typhoid Conjugate Vaccine in South Asia: Lessons From the Surveillance for Enteric Fever in Asia Project.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nelly MejiaGlobal Immunization Division, US Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Sarah W PallasGlobal Immunization Division, US Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Samir SahaChild Health Research Foundation, Dhaka, Bangladesh.
Jamal UdinChild Health Research Foundation, Dhaka, Bangladesh.
K M Ishtiaque SayeedChild Health Research Foundation, Dhaka, Bangladesh.
Denise O GarrettApplied Epidemiology, Sabin Vaccine Institute, Washington, DC, USA.
Kashmira DateGlobal Immunization Division, US Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Taiwo AbimbolaGlobal Immunization Division, US Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe conducted a cost of illness study to assess the economic burden of pediatric enteric fever (typhoid and paratyphoid) in Bangladesh. Results can inform public health policies to prevent enteric fever.

methodsThe study was conducted at 2 pediatric health facilities in Dhaka. For the patient and caregiver's perspective, we administered questionnaires on costs incurred from illness onset until the survey dates to caregivers of patients with blood culture positive cases at enrollment and 6 weeks later to estimate the direct medical, direct nonmedical, and indirect costs. From the perspective of the health care provider, we collected data on quantities and prices of resources used by the 2 hospitals to estimate the direct medical economic costs to treat a case of enteric fever. We collected costs in Bangladeshi takas and converted them into 2018 US dollars. We multiplied the unit cost per procedure by the frequency of procedures in the surveillance case cohort to calculate the average cost per case.

resultsAmong the 1772 patients from whom we collected information, the median cost of illness per case of enteric fever from the patient and caregiver perspective was US $64.03 (IQR: US $33.90 -$173.48). Median direct medical and nonmedical costs per case were 3% of annual labor income across the sample. From the perspective of the healthcare provider, the average direct medical cost per case was US $58.64 (range: US $37.25 at Hospital B, US $73.27 at Hospital A).

conclusionsOur results show substantial economic burden of enteric fever in Bangladesh, with higher costs for patients receiving inpatient care. As antimicrobial resistance increases globally, the cost of illness could increase, due to more expensive and potent drugs required for treatment.

Indexed as

Paratyphoid FeverTyphoid FeverAsiaBangladeshChildCost of IllnessHealth FacilitiesHumansBangladeshcost of illnessenteric feverparatyphoidTyphoid

Identifiers

PMID33258940
PMCPMC7750988

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.