Evidence map›Paper›PMID 33258593›Full record

ArticleThe Journal of organic chemistry2020

Fluorinated Carbohydrates as Lectin Ligands: Simultaneous Screening of a Monosaccharide Library and Chemical Mapping by

J Daniel Martínez, Ana I Manzano, Eva Calviño, Ana de Diego, Borja Rodriguez de Francisco, Cecilia Romanò, Stefan Oscarson, Oscar Millet, Hans-Joachim Gabius, Jesús Jiménez-Barbero and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Stereoselective Ferrier-Type O-Glycosylation Enabled by Difluoromethylated Glycal Donors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Obtaining PureThe Journal of organic chemistry · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Synthetic Approaches to Break the Chemical Shift Degeneracy of Glycans.Chembiochem : a European journal of chemical biology · 2022
    Article
  14. Review
  15. Article
  16. Pharmaceutics · 2022
    Article
  17. Article
  18. Automated Glycan Assembly ofAngewandte Chemie (International ed. in English) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

J Daniel MartínezCIC bioGUNE, Basque Research Technology Alliance, BRTA, Bizkaia Technology Park, Building 800, 48160 Derio, Spain.
Ana I ManzanoCentro de Investigaciones Biológicas Margarita Salas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
Eva CalviñoCentro de Investigaciones Biológicas Margarita Salas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
Ana de DiegoCentro de Investigaciones Biológicas Margarita Salas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
Borja Rodriguez de FranciscoCentro de Investigaciones Biológicas Margarita Salas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.ORCID 0000-0003-4778-313X
Cecilia RomanòCentre for Synthesis and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
Stefan OscarsonCentre for Synthesis and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.ORCID 0000-0002-8273-4918
Oscar MilletCIC bioGUNE, Basque Research Technology Alliance, BRTA, Bizkaia Technology Park, Building 800, 48160 Derio, Spain.ORCID 0000-0001-8748-4105
Hans-Joachim GabiusInstitute of Physiological Chemistry, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich, 80539 Munich, Germany.ORCID 0000-0003-3467-3900
Jesús Jiménez-BarberoCIC bioGUNE, Basque Research Technology Alliance, BRTA, Bizkaia Technology Park, Building 800, 48160 Derio, Spain.ORCID 0000-0001-5421-8513
Francisco J CañadaCentro de Investigaciones Biológicas Margarita Salas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.ORCID 0000-0003-4462-1469
Centro de Investigaciones Biológicas Margarita Salas · ESCIC bioGUNE · ESUniversity College Dublin · IECentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESIkerbasque · ESLudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular recognition of carbohydrates is a key step in essential biological processes. Carbohydrate receptors can distinguish monosaccharides even if they only differ in a single aspect of the orientation of the hydroxyl groups or harbor subtle chemical modifications. Hydroxyl-by-fluorine substitution has proven its merits for chemically mapping the importance of hydroxyl groups in carbohydrate-receptor interactions.

Identifiers

PMID33258593
PMCPMC7773211
OpenAlexW3107450772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.