Evidence map›Paper›PMID 33258422›Full record

Trial reportJournal of palliative care2023

African American Recruitment in Early Heart Failure Palliative Care Trials: Outcomes and Comparison With the ENABLE CHF-PC Randomized Trial.

Macy L Stockdill, J Nicholas Dionne-Odom, Rachel Wells, Deborah Ejem, Andres Azuero, Konda Keebler, Elizabeth Sockwell, Sheri Tims, Kathryn L Burgio, Sally Engler and 7 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of palliative care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02505425 (Randomized Trial of ENABLE CHF-PC for Heart Failure Patients and Caregivers.), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02505425 nacompletednot on this map

Randomized Trial of ENABLE CHF-PC for Heart Failure Patients and Caregivers. (Comprehensive Heartcare For Patients and Caregivers)

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2015 to 2019Enrolled573ConditionsHeart FailureArmsBehavioral Support, Usual HF Care
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Understanding Inclusion and Participation of People From Black African Diaspora Communities in Health and Care Research: A Realist Review.Health expectations : an international journal of public participation in health care and health policy · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Macy L StockdillSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0002-6138-6002
J Nicholas Dionne-OdomSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Rachel WellsSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0003-4447-012X
Deborah EjemSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Andres AzueroSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Konda KeeblerSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Elizabeth SockwellSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Sheri TimsSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Kathryn L BurgioDivision of Gerontology, Department of Medicine, Geriatrics, Palliative Care, University of Alabama at Birmingham, Birmingham, AL, USA.
Sally EnglerSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Raegan DurantDivision of Preventative Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Salpy V PamboukianDivision of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Jose TallajDivision of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Keith M SwetzDivision of Gerontology, Department of Medicine, Geriatrics, Palliative Care, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0001-9893-6517
Elizabeth KvaleDepartment of Medicine, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Rodney TuckerDepartment of Medicine, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Marie BakitasDivision of Gerontology, Geriatrics, and Palliative Care, Department of Medicine, School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USThe University of Texas at Austin · US

Funding

UAB Health Services Research (HSR) Training ProgramT32HS013852 · AHRQ · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEVITAN, EMILY B, MUGAVERO, MICHAEL J · 2003 to 2024
$8.0M
NRSA Training CoreTL1TR003106 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SAAG, KENNETH G · 2019 to 2023
$3.7M
ENABLE: CHF-PC (Comprehensive Heartcare For Patients and Caregivers)R01NR013665 · NINR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BAKITAS, MARIE ANNE · 2015 to 2019
$3.6M
An Upstream Palliative Care Intervention for Rural Family CaregiversR00NR015903 · NINR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ODOM, JAMES N. · 2018 to 2020
$727k
An Upstream Palliative Care Intervention for Rural Family CaregiversK99NR015903 · NINR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ODOM, JAMES N. · 2016 to 2017
$189k
Influence of Race, Gender, Rurality, and Dyadic Health on Symptom Trajectories in Persons with Advanced Heart FailureF31NR018782 · NINR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STOCKDILL, MACY L · 2019 to 2021
$63k
AHRQ HHS T32 HS013852NCATS NIH HHS TL1 TR003106NINR NIH HHS F31 NR018782NINR NIH HHS K99 NR015903NINR NIH HHS R00 NR015903NINR NIH HHS R01 NR013665
6 · The paper itself

Abstract

backgroundPalliative care trial recruitment of African Americans (AAs) is a formidable research challenge.

objectivesExamine AA clinical trial recruitment and enrollment in a palliative care randomized controlled trial (RCT) for heart failure (HF) patients and compare patient baseline characteristics to other HF palliative care RCTs.

methodsThis is a descriptive analysis the ENABLE CHF-PC (Educate, Nurture, Advise, Before Life Ends: Comprehensive Heartcare for Patients and Caregivers) RCT using bivariate statistics to compare racial and patient characteristics and differences through recruitment stages. We then compared the baseline sample characteristics among three palliative HF trials.

resultsOf 785 patients screened, 566 eligible patients with NYHA classification III-IV were approached; 461 were enrolled and 415 randomized (AA = 226). African Americans were more likely to consent than Caucasians (55%;

conclusionENABLE CHF-PC has the highest reported recruitment rate and proportion of AAs in a palliative clinical trial to date. Community-based recruitment partnerships, recruiter training, ongoing communication with recruiters and clinician co-investigators, and recruiter racial concordance likely contributed to successful recruitment of AAs. These important insights provide guidance for design of future HF palliative RCTs.

trial registrationClinicalTrials.gov Identifier: NCT02505425.

Indexed as

Heart FailureHospice and Palliative Care NursingBlack or African AmericanHumansPalliative CareQuality of Lifeheart failureKCCQpalliative careRCTrecruitment strategies

Identifiers

PMID33258422
PMCPMC8314978
OpenAlexW3107653601

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.