Evidence map›Paper›PMID 33258320›Full record

ArticleKorean circulation journal2020

Morbidity and Mortality of Very Low Birth Weight Infants with Congenital Heart Disease.

Woo Sun Song, Chae Young Kim, Byong Sop Lee, Ellen Ai Rhan Kim, Ki Soo Kim, Euiseok Jung

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Korean circulation journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Woo Sun SongDepartment of Pediatrics, University of Eulji College of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0001-7894-5213
Chae Young KimDepartment of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, Korea.ORCID https://orcid.org/0000-0002-9905-6519
Byong Sop LeeDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-1347-4200
Ellen Ai Rhan KimDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-9859-3021
Ki Soo KimDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-1547-5220
Euiseok JungDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, Seoul, Korea. euisjung@amc.seoul.kr.ORCID https://orcid.org/0000-0003-0693-5627
Asan Medical Center · KREulji University · KRKyung Hee University Hospital at Gangdong · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThis study aimed to provide morbidity and mortality information on very low birth weight (VLBW) infants with congenital heart disease (CHD-VLBWs).

methodsThe study used a 10-year cohort of VLBW infants from a single institution. CHD was classified according to International Classification of Diseases, Version 9, Clinical Modification. Mortality and neonatal outcomes were assessed by comparing the CHD-VLBWs with gestational age- and birth weight-matched controls.

resultsThe prevalence of CHD-VLBWs was 7.5% (79/1,050), mean gestational age was 31.1±3.2 weeks, and mean birth weight was 1,126.2±268.3 g; 50.6% of the infants were small for the gestational age. The CHD-VLBWs more commonly had bronchopulmonary dysplasia (BPD), and the longer they were exposed to oxygen, the more frequently they developed BPD. Those with cyanotic heart disease developed severe BPD more frequently. Necrotizing enterocolitis (NEC) occurred frequently in the CHD-VLBWs and was not associated with their feeding patterns. CHD-VLBWs had a higher mortality rate; prematurity-related diseases were the leading cause of death before surgery, while heart-related problems were the leading cause of death after surgery. We found no significant difference in mortality from prematurity-related disease between the CHD-VLBWs and controls. In the subgroup analysis of CHD, the cyanotic CHD group had a higher incidence of BPD and higher mortality rate than the acyanotic CHD group.

conclusionsCHD-VLBWs showed higher BPD, NEC, and mortality rates than those without CHD. There was also a higher incidence of BPD and mortality in VLBW infants with cyanotic CHD than in those with acyanotic CHD.

Indexed as

Bronchopulmonary dysplasiaCongenital heart defectNecrotizing enterocolitisPreterm infantsVery-low-birth-weight infant

Identifiers

PMID33258320
PMCPMC7707980
OpenAlexW3096340417

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.