ArticleEye (London, England)2021
Phenotyping of retinal neovascularization in ischemic retinal vein occlusion using wide field OCT angiography.
Article in Eye (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Retinal neovascularization detection from fundus images using deformable attention ResNet and swarm-hiking optimization.International ophthalmology · 2026Article
- Intravitreal Dexamethasone Implant in Retinal Vein Occlusion: A Pilot Study Exploring Baseline Ocular and Circulating Biomarkers.International journal of molecular sciences · 2026Article
- Inorganic nanomaterials as promising therapeutic agents for ocular neovascularization: Progress and perspectives.Materials today. Bio · 2025Review
- Widefield OCT angiography.Progress in retinal and eye research · 2025Review
- Naringin Suppresses CoClAntioxidants (Basel, Switzerland) · 2025Article
- Advantages of the Utilization of Wide-Field OCT and Wide-Field OCT Angiography in Clinical Practice.Diagnostics (Basel, Switzerland) · 2024Review
- Article
- A Complete Review of Automatic Detection, Segmentation, and Quantification of Neovascularization in Optical Coherence Tomography Angiography Images.Diagnostics (Basel, Switzerland) · 2023Review
- Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF.Journal of nanobiotechnology · 2023Article
- Clinical utility of ultra-widefield fluorescein angiography and optical coherence tomography angiography for retinal vein occlusions.Frontiers in medicine · 2023Review
- Deep-learning-based AI for evaluating estimated nonperfusion areas requiring further examination in ultra-widefield fundus images.Scientific reports · 2022Article
- The Role of Widefield and Ultra Widefield Optical Coherence Tomography in the Diagnosis and Management of Vitreoretinal Diseases.Diagnostics (Basel, Switzerland) · 2022Article
- Review: The Development of Risk Factors and Cytokines in Retinal Vein Occlusion.Frontiers in medicine · 2022Review
- Progress and Challenges of Anti-VEGF Agents and Their Sustained-Release Strategies for Retinal Angiogenesis.Drug design, development and therapy · 2022Review
- Multimodal Imaging of Microvascular Abnormalities in Retinal Vein Occlusion.Journal of clinical medicine · 2021Review
- Characterizing Flow and Structure of Diabetic Retinal Neovascularization after Intravitreal Anti-VEGF Using Optical Coherence Tomography Angiography: A Pilot Study.Journal of ophthalmology · 2021Article
- Role of optical coherence tomography angiography in the evaluation of peripheral ischemia in retinal vein occlusion.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
- Optical coherence tomography imaging of the peripheral retina.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
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Authors and funding
10 authors at 1 institution in 3 countries.
Funding
Abstract
BACKGROUND/
objectivesAbnormal retinal neovascularization caused by ischemic retinal vein occlusion (RVO) is a frequent cause of visually significant vitreous hemorrhage. The early detection of new vessels may be challenging and often requires the use of invasive tests such as fundus fluorescein angiography (FA). We demonstrate the use of wide-field optical coherence tomography angiography (WF-OCTA) in the detection and characterization of neovascularization secondary to ischemic RVO. SUBJECTS/
methodsWe conducted a retrospective observational case series of patients diagnosed with ischemic RVO between August 2018 and March 2019, who underwent WF-SS-OCTA imaging (PLEX Elite 9000, Carl Zeiss Meditec). We performed real-life montage imaging, covering the involved area and compared the findings of WF-SS-OCTA to standard clinical examination and when available, ultrawide-field fluorescein angiography (UWF-FA, Optos 200TX).
resultsIn the included 39 eyes with ischemic RVO, neovascularization elsewhere (NVE) was encountered in 16 of 39 eyes (41%) on WF-OCTA and were characterized as sea-fan type vessels and nodular type vessels, based on their appearance and localization. NVE was identified in 4/39 eyes on standard clinical examination, equating to a detection rate of 10.3%. All were of a sea-fan morphology. In one case, NVE found on WF-OCTA was not observed on UWF-FA, which was a nodular type. Neovascularization of the disc (NVD) was detected in one eye.
conclusionsWF-OCTA may become a useful noninvasive tool in the detection of neovascularization in patients with ischemic RVO. Furthermore, the characterization of different morphologies of neovascularization detected by WF-OCTA could be of clinical relevance.
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