ArticleScientific reports2020
Wide-ranging transcriptomic analysis of Poncirus trifoliata, Citrus sunki, Citrus sinensis and contrasting hybrids reveals HLB tolerance mechanisms.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Amicoumacins produced by the native citrus microbiome isolateApplied and environmental microbiology · 2025Article
- Exploring the biochemical and molecular mechanisms that contribute to Huanglongbing (HLB) tolerance in Citrus australis hybrids.BMC genomics · 2025Article
- Fertilization Strategies in Huanglongbing-InfectedPlants (Basel, Switzerland) · 2025Article
- Review
- Transcriptomic and biochemical analysis of pummelo x finger lime hybrids in response to Huanglongbing (HLB).BMC plant biology · 2025Article
- Novel citrus hybrids incorporating Australian lime genetics: development of HLB-tolerant citrus rootstocks and physiological changes in 'Valencia' sweet orange scions.Frontiers in plant science · 2025Article
- Comparative Transcriptome and sRNAome Analysis Suggest Coordinated Citrus Immune Responses against Huanglongbing Disease.Plants (Basel, Switzerland) · 2024Article
- Co-expression network analysis and identification of core genes in the interaction between wheat and Puccinia striiformis f. sp. tritici.Archives of microbiology · 2024Article
- Plant volatile-triggered defense in citrus against biotic stressors.Frontiers in plant science · 2024Article
- Insights into the Molecular Basis of Huanglongbing Tolerance in Persian Lime (International journal of molecular sciences · 2023Article
- CRISPR technology towards genome editing of the perennial and semi-perennial crops citrus, coffee and sugarcane.Frontiers in plant science · 2023Review
- Comparative transcriptome profiling of susceptible and tolerant citrus species at early and late stage of infection by "Frontiers in plant science · 2023Article
- Poor shoot and leaf growth in Huanglongbing-affected sweet orange is associated with increased investment in defenses.Frontiers in plant science · 2023Article
- Candidatus Liberibacter asiaticus accumulation in the phloem inhibits callose and reactive oxygen species.Plant physiology · 2022Article
- Insights into the mechanism of Huanglongbing tolerance in the Australian finger lime (Frontiers in plant science · 2022Article
- An Overview of the Mechanisms Against "Frontiers in microbiology · 2022Review
- Molecular signatures between citrus and Candidatus Liberibacter asiaticus.PLoS pathogens · 2021Review
- SuperSour: A New Strategy for Breeding Superior Citrus Rootstocks.Frontiers in plant science · 2021Review
- Controlling Citrus Huanglongbing: Green Sustainable Development Route Is the Future.Frontiers in plant science · 2021Review
- Article
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9 authors.
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Abstract
Huanglongbing (HLB), caused mainly by 'Candidatus Liberibacter asiaticus' (CLas), is the most devastating citrus disease because all commercial species are susceptible. HLB tolerance has been observed in Poncirus trifoliata and their hybrids. A wide-ranging transcriptomic analysis using contrasting genotypes regarding HLB severity was performed to identify the genetic mechanism associated with tolerance to HLB. The genotypes included Citrus sinensis, Citrus sunki, Poncirus trifoliata and three distinct groups of hybrids obtained from crosses between C. sunki and P. trifoliata. According to bacterial titer and symptomatology studies, the hybrids were clustered as susceptible, tolerant and resistant to HLB. In P. trifoliata and resistant hybrids, genes related to specific pathways were differentially expressed, in contrast to C. sinensis, C. sunki and susceptible hybrids, where several pathways were reprogrammed in response to CLas. Notably, a genetic tolerance mechanism was associated with the downregulation of gibberellin (GA) synthesis and the induction of cell wall strengthening. These defense mechanisms were triggered by a class of receptor-related genes and the induction of WRKY transcription factors. These results led us to build a hypothetical model to understand the genetic mechanisms involved in HLB tolerance that can be used as target guidance to develop citrus varieties or rootstocks with potential resistance to HLB.
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