ArticleNature communications2020
Enhanced dispersion stability of gold nanoparticles by the physisorption of cyclic poly(ethylene glycol).
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
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- Decoupling Colloidal Stability and Catalytic Activity of Gold Nanocatalysts via In-Situ Sacrificial Physisorbed PEG Coatings.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Gold-incorporated hyaluronic acid nanoparticles enhance ablative radiotherapy efficacy in lung cancer.International journal of pharmaceutics: X · 2026Article
- Plasmonic glyco-nanoparticles for single-test multiplexed detection and differentiation of cancer cells.Nanoscale · 2026Article
- Novel Gold-Functionalization of Liposomes and Its Impact on Cellular Uptake and Trafficking.Molecular pharmaceutics · 2026Article
- Alexidine, identified as a Z-DNA inducer by the NanoZ screening platform, acts as a transcriptional regulator.Nucleic acids research · 2026Article
- Core-Shell Plasmonic Nanocomposites with Synergistic Photothermal and Photochemical Activity for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2026Review
- Expedient Access to Gold/Quantum-Dot Nanohybrids Mediated by Poly(ethylene Glycol) Ligands of Distinct Macromolecular Architecture.Macromolecular rapid communications · 2026Article
- Targeted Phototriggered and pH-Responsive Micellar Cancer Drug Delivery System with Real-Time Monitoring through the NSET Mechanism.ACS applied bio materials · 2025Article
- Unraveling Lyophilization and Redispersion Effects on Miktoarm Polymer-Based Nanoformulations.International journal of molecular sciences · 2025Article
- Exploring the Coating of Gold Nanoparticles with Lipids.Nanomaterials (Basel, Switzerland) · 2025Article
- Role of Polymeric Stabilizing Agents as a Molecular Spacer in Gold Nanoparticle-Mediated FRET-Based Biosensing.Biosensors · 2025Review
- Preparation of mitochondria-targeted gold nanoprobes and their SERS application in the detection of DON-induced apoptosis.Analytical and bioanalytical chemistry · 2025Article
- Ultrashort Peptides as Stabilizing Agents for Colloidal Nanogold.ACS applied materials & interfaces · 2025Article
- The Art of PEGylation: From Simple Polymer to Sophisticated Drug Delivery System.International journal of molecular sciences · 2025Review
- Article
- The Effect of the Size of Gold Nanoparticle Contrast Agents on CT Imaging of the Gastrointestinal Tract and Inflammatory Bowel Disease.Bioconjugate chemistry · 2025Article
- Gold Nanoraspberries for Surface-Enhanced Raman Scattering: Synthesis, Optimization, and Characterization.ACS omega · 2025Article
- Recent development of micro-nano carriers for oral antineoplastic drug delivery.Materials today. Bio · 2025Review
- The Preparation of Cyclic Binary Block Polymer Using Bimolecular Homodifunctional Coupling Reaction and Characterization of Its Performance as a Drug Carrier.Molecules (Basel, Switzerland) · 2025Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors.
Funding
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Abstract
Nano-sized metal particles are attracting much interest in industrial and biomedical applications due to the recent progress and development of nanotechnology, and the surface-modifications by appropriate polymers are key techniques to stably express their characteristics. Herein, we applied cyclic poly(ethylene glycol) (c-PEG), having no chemical inhomogeneity, to provide a polymer topology-dependent stabilization for the surface-modification of gold nanoparticles (AuNPs) through physisorption. By simply mixing c-PEG, but not linear counterparts, enables AuNPs to maintain dispersibility through freezing, lyophilization, or heating. Surprisingly, c-PEG endowed AuNPs with even better dispersion stability than thiolated PEG (HS-PEG-OMe). The stronger affinity of c-PEG was confirmed by DLS, ζ-potential, and FT-IR. Furthermore, the c-PEG system exhibited prolonged blood circulation and enhanced tumor accumulation in mice. Our data suggests that c-PEG induces physisorption on AuNPs, supplying sufficient stability toward bio-medical applications, and would be an alternative approach to the gold-sulfur chemisorption.
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