Evidence map›Paper›PMID 33257568›Full record

Observational studyProceedings of the National Academy of Sciences of the United States of America2020

Valuation of peers' safe choices is associated with substance-naïveté in adolescents.

Dongil Chung, Mark A Orloff, Nina Lauharatanahirun, Pearl H Chiu, Brooks King-Casas

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Article
  6. Determinants of Rule-Breaking in Adolescence.Journal of adolescence · 2025
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  16. Social influence in adolescence as a double-edged sword.Proceedings. Biological sciences · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Dongil ChungFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA 24016.
Mark A OrloffFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA 24016.ORCID 0000-0002-6958-5479
Nina LauharatanahirunFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA 24016.
Pearl H ChiuFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA 24016; chiup@vtc.vt.edu bkcasas@vtc.vt.edu.ORCID 0000-0002-8767-7406
Brooks King-CasasFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA 24016; chiup@vtc.vt.edu bkcasas@vtc.vt.edu.
Biomedical Research Institute · US

Funding

Neurobehavioral Determinants of Health Risk Behaviors: From Adolescence to Young AdulthoodR01DA036017 · NIDA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CASAS, BROOKS, KIM-SPOON, JUNGMEEN · 2013 to 2022
$7.2M
Neurobehavioral Mechanisms of Social Dysfunction in Borderline Personality DisorderR01MH115221 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CASAS, BROOKS · 2018 to 2022
$3.3M
Direct sub-second measurement of neuromodulator signaling during risky decision-makingR01MH122948 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CASAS, BROOKS, MONTAGUE, P READ · 2020 to 2024
$3.3M
Neuroimaging Major Depression and Nicotine Dependence on Axes of ValuationR01MH091872 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CHIU, PEARL H · 2010 to 2014
$1.8M
Neural mechanisms of social influence on risky decisions in cocaine dependenceR21DA042274 · NIDA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CHIU, PEARL H, CHUNG, DONGIL · 2017 to 2018
$443k
NIDA NIH HHS R01 DA036017NIDA NIH HHS R21 DA042274NIMH NIH HHS R01 MH091872NIMH NIH HHS R01 MH115221NIMH NIH HHS R01 MH122948
6 · The paper itself

Abstract

Social influences on decision-making are particularly pronounced during adolescence and have both protective and detrimental effects. To evaluate how responsiveness to social signals may be linked to substance use in adolescents, we used functional neuroimaging and a gambling task in which adolescents who have and have not used substances (substance-exposed and substance-naïve, respectively) made choices alone and after observing peers' decisions. Using quantitative model-based analyses, we identify behavioral and neural evidence that observing others' safe choices increases the subjective value and selection of safe options for substance-naïve relative to substance-exposed adolescents. Moreover, the effects of observing others' risky choices do not vary by substance exposure. These results provide neurobehavioral evidence for a role of positive peers (here, those who make safer choices) in guiding adolescent real-world risky decision-making.

Indexed as

Choice BehaviorPeer InfluenceAdolescentAdolescent BehaviorFemaleHealthy LifestyleHumansMaleRisk-TakingSocial PerceptionSubstance-Related Disordersadolescentdecision-makingpeer influencesocial influencesubstance use

Identifiers

PMID33257568
PMCPMC7749349
OpenAlexW3110443518

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.