Evidence map›Paper›PMID 33257549›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

An angular motion of a conserved four-helix bundle facilitates alternating access transport in the TtNapA and EcNhaA transporters.

Gal Masrati, Ramakanta Mondal, Abraham Rimon, Amit Kessel, Etana Padan, Erik Lindahl, Nir Ben-Tal

Abstract readVideo-Audio Media
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. pH-dependent activation of the NaNature communications · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Prokaryotic NaInternational journal of molecular sciences · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gal MasratiDepartment of Biochemistry and Molecular Biology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv 69978, Israel.ORCID 0000-0003-1322-5762
Ramakanta MondalDepartment of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 91904 Jerusalem, Israel.ORCID 0000-0002-0798-5995
Abraham RimonDepartment of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 91904 Jerusalem, Israel.
Amit KesselDepartment of Biochemistry and Molecular Biology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv 69978, Israel.ORCID 0000-0003-0227-0226
Etana PadanDepartment of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 91904 Jerusalem, Israel.
Erik LindahlScience for Life Laboratory, Stockholm University & KTH Royal Institute of Technology, 171 65 Solna, Sweden.
Nir Ben-TalDepartment of Biochemistry and Molecular Biology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv 69978, Israel; bental@tauex.tau.ac.il.ORCID 0000-0001-6901-832X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is ongoing debate regarding the mechanism through which cation/proton antiporters (CPAs), like

Indexed as

Cell MembraneCrystallography, X-RayEscherichia coli ProteinsMolecular Dynamics SimulationProtein Conformation, alpha-HelicalProtein DomainsProtonsSodiumSodium-Hydrogen ExchangersThermus thermophilusEscherichia coli ProteinsNhaA protein, E coliProtonsSodiumSodium-Hydrogen Exchangerscation/proton antiporterselevator mechanismmolecular dynamicsNhaArocking bundle mechanism

Identifiers

PMID33257549
PMCPMC7749304

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.