Evidence map›Paper›PMID 33257505›Full record

ArticleMolecular and cellular biology2021

The N-Terminal Tail of Histone H3 Regulates Copper Homeostasis in Saccharomyces cerevisiae.

Sakshi Singh, Rakesh Kumar Sahu, Raghuvir Singh Tomar

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sakshi Singh *Laboratory of Chromatin Biology, Department of Biological Sciences, Indian Institute of Science Education and Research Bhopal, Bhopal, India.
Rakesh Kumar Sahu *Laboratory of Chromatin Biology, Department of Biological Sciences, Indian Institute of Science Education and Research Bhopal, Bhopal, India.
Raghuvir Singh TomarLaboratory of Chromatin Biology, Department of Biological Sciences, Indian Institute of Science Education and Research Bhopal, Bhopal, India rst@iiserb.ac.in.ORCID 0000-0002-3574-7839
Indian Institute of Science Education and Research, Bhopal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Copper homeostasis is crucial for various cellular processes. The balance between nutritional and toxic copper levels is maintained through the regulation of its uptake, distribution, and detoxification via antagonistic actions of two transcription factors, Ace1 and Mac1. Ace1 responds to toxic copper levels by transcriptionally regulating detoxification genes

Indexed as

Gene Expression Regulation, FungalAmino Acid SequenceCopperDNA-Binding ProteinsHistone AcetyltransferasesHistonesHomeostasisMetallothioneinMutationNuclear ProteinsPromoter Regions, GeneticProtein BindingSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionStress, PhysiologicalCopperCRS5 protein, S cerevisiaeCUP1-1 protein, S cerevisiaeCUP2 protein, S cerevisiaeDNA-Binding ProteinsHistone AcetyltransferasesHistonesMAC1 protein, S cerevisiaeMetallothioneinNuclear ProteinsSaccharomyces cerevisiae ProteinsSPT10 protein, S cerevisiaeSPT15 protein, S cerevisiaeTATA-Box Binding ProteinTranscription FactorsAce1coppercopper responseCup1 metallothioneinepigeneticshistone modificationhistonesmetal homeostasisprotein aggregationtranscription regulationyeast

Identifiers

PMID33257505
PMCPMC8093488
OpenAlexW3108912358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.