Evidence map›Paper›PMID 33257408›Full record

ArticleJournal for immunotherapy of cancer2020

Louis Lantier, Agathe Poupée-Beaugé, Anne di Tommaso, Céline Ducournau, Mathieu Epardaud, Zineb Lakhrif, Stéphanie Germon, Françoise Debierre-Grockiego, Marie-Noëlle Mévélec, Arthur Battistoni and 10 more

Open access · goldAbstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Microorganisms · 2026
    Review
  2. Article
  3. Review
  4. Molecular therapy. Oncology · 2025
    Article
  5. Review
  6. Computational vaccine development against protozoa.Computational and structural biotechnology journal · 2025
    Review
  7. The anticancer mechanisms ofCancer biology & therapy · 2024
    Article
  8. Parasites revive hope for cancer therapy.European journal of medical research · 2024
    Review
  9. Review
  10. Article
  11. Nasal administration of recombinantJournal for immunotherapy of cancer · 2023
    Article
  12. International journal of molecular sciences · 2022
    Article
  13. Article
  14. Anti-Tumor Effect of Parasitic Protozoans.Bioengineering (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 2 countries.

Louis LantierUniversité de Tours, INRAE, ISP, F-37000, Tours, France louis.lantier@univ-tours.fr.ORCID 0000-0003-3642-7500
Agathe Poupée-BeaugéUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Anne di TommasoUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Céline DucournauUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Mathieu EpardaudINRAE, Université de Tours, ISP, F-37380, Nouzilly, France.
Zineb LakhrifUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Stéphanie GermonUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Françoise Debierre-GrockiegoUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Marie-Noëlle MévélecINRAE, Université de Tours, ISP, F-37380, Nouzilly, France.
Arthur BattistoniUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Loïs CoënonUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Nora Deluce-Kakwata-NkorEA 4245 Cellules Dendritiques, Immuno-Modulation et Greffes, F-37000, Universite de Tours, Tours, France.
Florence Velge-RousselEA 4245 Cellules Dendritiques, Immuno-Modulation et Greffes, F-37000, Universite de Tours, Tours, France.
Céline BeauvillainInserm U1232, Faculté des Sciences, CRCINA, CHU d'Angers, Université Angers, Angers, France.
Thomas BaranekINSERM, Centre d'Etude des Pathologies Respiratoires (CEPR), UMR, 1100, Université de Tours, Tours, France.
Gordon Scott LeeKymeris Santé, SA, F-37000, Tours, France.
Thibault KervarrecUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Antoine TouzéUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Nathalie MoiréINRAE, Université de Tours, ISP, F-37380, Nouzilly, France.
Isabelle Dimier-PoissonUniversité de Tours, INRAE, ISP, F-37000, Tours, France.
Université de Tours · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicroorganisms that can be used for their lytic activity against tumor cells as well as inducing or reactivating antitumor immune responses are a relevant part of the available immunotherapy strategies. Viruses, bacteria and even protozoa have been largely explored with success as effective human antitumor agents. To date, only one oncolytic virus-T-VEC-has been approved by the US Food and Drug Administration for use in biological cancer therapy in clinical trials. The goal of our study is to evaluate the potential of a livestock pathogen, the protozoan METHODS/

resultsWe demonstrated that the treatment of murine thymoma EG7 by subcutaneous injection of

conclusionThese results highlight

Indexed as

AnimalsBiological ProductsDisease Models, AnimalFemaleHumansMiceNeoplasmsNeosporaBiological Productscellularimmunityimmunotherapy

Identifiers

PMID33257408
PMCPMC7705568
OpenAlexW3107443730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.