Evidence map›Paper›PMID 33257364›Full record

ArticleBMJ case reports2020

Unilateral nipple discharge in a man without a palpable mass diagnosed as breast cancer.

Karan N Ramakrishna, Justin Durland, Christopher Ramos, Amit Singh Dhamoon

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Karan N RamakrishnaDepartment of Internal Medicine, SUNY Upstate Medical University, Syracuse, New York, USA.
Justin DurlandDepartment of Internal Medicine, SUNY Upstate Medical University, Syracuse, New York, USA.
Christopher RamosDepartment of Internal Medicine, SUNY Upstate Medical University, Syracuse, New York, USA.
Amit Singh DhamoonDepartment of Internal Medicine, SUNY Upstate Medical University, Syracuse, New York, USA dhamoona@upstate.edu.
SUNY Upstate Medical University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 69-year-old man without a family history of breast cancer presented to his primary care physician with a 1-year history of clear, unilateral nipple discharge (ND) without an associated palpable breast mass. His laboratory findings were significant for hyperprolactinaemia at 28 ng/mL. Diagnostic work up including mammography, ultrasound and core needle biopsy ultimately revealed a ductal carcinoma in situ and a rare papillary variant of invasive ductal carcinoma. The patient was referred to a multidisciplinary oncology team and underwent a right total mastectomy followed by adjuvant hormonal therapy. The patient made a good postoperative recovery and remains without evidence of recurrence 6 months from surgery. Male breast cancer is rare, but its incidence is increasing. Male breast cancer presenting as ND without a palpable mass is uncommon. Early recognition of breast symptoms in men can lead to earlier diagnoses and improved outcomes.

Indexed as

Nipple DischargeAgedAntineoplastic Agents, HormonalBiopsy, Large-Core NeedleBreast Neoplasms, MaleCarcinoma, Intraductal, NoninfiltratingCarcinoma, PapillaryCombined Modality TherapyHumansMaleMastectomyNeoplasms, Multiple PrimaryTamoxifenAntineoplastic Agents, HormonalTamoxifenbreast cancercancer intervention

Identifiers

PMID33257364
PMCPMC7705368
OpenAlexW3106753459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.