Evidence map›Paper›PMID 33257254›Full record

SynthesisCardiovascular revascularization medicine : including molecular interventions2021

Does Pulmonary Embolism in Critically Ill COVID-19 Patients Worsen the In-Hospital Mortality: A Meta-Analysis.

Tanveer Mir, Hassan Bin Attique, Yasar Sattar, Neelambuj Regmi, Muhammad Shayan Khan, Haris Youns, Basharat Qayoom, Michael T Jerger, M Chadi Alraies

Abstract readMeta-Analysis
In one paragraph

Synthesis in Cardiovascular revascularization medicine : including molecular interventions, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tanveer MirInternal Medicine Detroit Medical Center, Wayne State University, Detroit, USA. Electronic address: gr6723@wayne.edu.
Hassan Bin AttiqueInternal Medicine, University of Connecticut, Farmington, USA.
Yasar SattarIcahn School of Medicine at Mount Sinai Elmhurst Hospital, New York, USA.
Neelambuj RegmiDepartment of Pulmonary and Critical Care, Detroit Medical Center/Wayne State University, USA.
Muhammad Shayan KhanMercy Saint Vincent Medical Centre, Toledo, OH, USA.
Haris YounsInternal Medicine Detroit Medical Center, Wayne State University, Detroit, USA.
Basharat QayoomGovernment Medical College, Srinagar, India.
Michael T JergerDepartment of Pulmonary and Critical Care, Detroit Medical Center/Wayne State University, USA.
M Chadi AlraiesDetroit Medical Center, Detroit, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMortality in critically ill COVID (coronavirus disease) patients secondary to pulmonary embolism (PE) has conflicting data. We aim to evaluate the mortality outcomes of critically ill patients with and without PE (WPE).

methodsThree studies were identified after a digital database search on PE in ICU (intensive care unit) patients until September 2020. The primary outcome was mortality. Outcomes were compared using a random method odds ratio and confidence interval of 95%.

resultsA total of 439 patients were included in the study. Diabetes, hypertension, and renal replacement requirement had no statistically significant association between PE and WPE, p = 0.39, p = 0.23, and p = 0.29 respectively. The study revealed that males have higher odds of PE, OR-1.98, 95%CI-1.01-3.89; p = 0.05. In-hospital mortality results were comparable between PE and WPE after subgroup analysis and correction of heterogeneity, p = 0.25.

conclusionPE in critically ill COVID patients had similar in-hospital mortality outcomes as WPE patients. The findings are only hypotheses generated from observational studies and need future randomized, prospective clinical trials for a definitive conclusion.

Indexed as

COVID-19Pulmonary EmbolismCritical IllnessFemaleHospital MortalityHumansMaleProspective StudiesSARS-CoV-2CoronavirusCritically ill patientsPulmonary embolism

Identifiers

PMID33257254
PMCPMC7687401

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.