ArticleDrug and alcohol dependence2021
Association of fatty acid ethyl esters in meconium with behavior during childhood.
Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Trust but verify…the importance of multimethod and biomarker assessments of prenatal substance exposures.Pediatric research · 2026Article
- Fatty acid ethyl esters in meconium and language development at 10 and 12 years.Pediatric research · 2026Article
- Prenatal Alcohol Exposure Predicts Academic Outcomes from Childhood to Adolescence: A Prospective Longitudinal Study Based on Meconium Ethyl Glucuronide.Behavioral sciences (Basel, Switzerland) · 2026Article
- Internal assets in low-income urban adolescents from 12 to 17 years: Gender variation.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025Article
- Prenatal cocaine exposure and self-reported behavioral adjustments from ages 12 to 21: environmental pathways.Psychological medicine · 2024Article
- Analysis for different flavor compounds in mature milk from human and livestock animals by GC × GC-TOFMS.Food chemistry: X · 2023Article
- Comprehensive Genome and Transcriptome Analysis Identifies SLCO3A1 Associated with Aggressive Behavior in Pigs.Biomolecules · 2023Article
- Prenatal cocaine exposure and substance use disorder in emerging adulthood at age 21.Drug and alcohol dependence · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo examine associations between amounts of fatty acid ethyl esters (FAEEs) in meconium and behavior in school aged children exposed to alcohol and drugs in utero.
methodsA secondary analysis of a prospective cohort of cocaine, polydrug exposed children, primarily African-American, low socioeconomic status, recruited at birth into a longitudinal study. FAEEs were quantified with gas chromatography via a flame ionization detector. Meconium was analyzed for FAEEs for 216 newborns of whom 194 were assessed with the Child Behavior Checklist (CBCL) at ages 4, 6, 9, 10, 11, and 12. Generalized estimating equation analyses were used to assess the relationship of quantity of FAEEs to outcomes, controlling for maternal psychological distress.
resultsHigher concentrations of FAEEs (ethyl myristate, ethyl palmitate, ethyl oleate, ethyl linoleate, and ethyl linolenate) were associated with caregiver reported aggressive and/or delinquent behavior at ages 10 and 12. After control for caregiver psychological distress, and age, significant (p < 0.05) FAEE by age interactions were found for ethyl myristate for aggression and for ethyl oleate, ethyl linoleate and ethyl linolenate for delinquency. Thus, higher concentrations of FAEE were related to more caregiver reported aggressive and delinquent behaviors of clinical significance at ages 10 and 12.
conclusionHigher concentrations of FAEEs in meconium are potential markers for children at risk for aggressive and delinquent behaviors related to the effects of prenatal alcohol exposure.
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