SynthesisJournal of orthopaedic surgery and research2020
Association between metabolic syndrome and venous thromboembolism after total joint arthroplasty: a meta-analysis of cohort studies.
Synthesis in Journal of orthopaedic surgery and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- A nomogram for assessing the risk of deep vein thrombosis following surgery for pilon fractures.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026Article
- Metabolic Syndrome as a Risk Factor for Postoperative Complication in Patients Undergoing Spine Surgery: A Systematic Review and Meta-Analysis of More Than 3 Million Cases.International journal of spine surgery · 2025Article
- Metabolic syndrome, adipokines, coagulation factors, and venous thromboembolism: a two-step Mendelian randomization study.Diabetology & metabolic syndrome · 2025Article
- Basic science research opportunities in thrombosis and hemostasis: Communication from the SSC of the ISTH.Journal of thrombosis and haemostasis : JTH · 2022Article
- The deep vein thrombosis of lower limb after total hip arthroplasty: what should we care.BMC musculoskeletal disorders · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMetabolic syndrome (MetS) has been associated with hypercoagulative status. However, previous studies evaluating the association between MetS and incidence of venous thromboembolism (VTE) after total joint arthroplasty (TJA) showed inconsistent results. We performed a meta-analysis to evaluate the influence of MetS on the risk of VTE following TJA.
methodsCohort studies were identified by the search of PubMed, Embase, and the Cochrane's Library databases. A random-effect model was used if considerable heterogeneity was detected; otherwise, a fixed-effect model was used. Subgroup analyses according to the category of VTE, definition of MetS, category of procedure, and follow-up durations were performed.
resultsSeven cohort studies with 1,341,457 patients that underwent TJA were included, with 118,060 MetS patients (8.8%) at baseline. With a follow-up duration up to 3 months after surgery, 9788 patients had VTE. Pooled results with a random-effect model showed that MetS was not associated with increased overall VTE after TJA (adjusted risk ratio [RR] = 1.24, 95% confidence interval [CI] 0.89 ~ 1.72, p = 0.20; I
conclusionsCurrent evidence from observational studies suggests MetS might be associated with an increased risk of DVT but not PE after TJA.
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