Evidence map›Paper›PMID 33256689›Full record

ArticleBMC musculoskeletal disorders2020

Risk factors for cement leakage and nomogram for predicting the intradiscal cement leakage after the vertebra augmented surgery.

Tian-Yu Zhang, Pei-Xun Zhang, Feng Xue, Dian-Ying Zhang, Bao-Guo Jiang

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Anterior thoracolumbar column reconstruction with the vertebral body stent-safety and efficacy.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. A nomogram for short-term recurrent pain after percutaneous vertebroplasty for osteoporotic vertebral compression fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Exploration of percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fracture as day surgery: a retrospective study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tian-Yu ZhangDepartment of Traumatic Orthopaedics, Peking University People's Hospital, No.11 South Avenue, Xi Zhi Men, Xicheng District, Beijing, 100044, China.
Pei-Xun ZhangDepartment of Traumatic Orthopaedics, Peking University People's Hospital, No.11 South Avenue, Xi Zhi Men, Xicheng District, Beijing, 100044, China.
Feng XueDepartment of Traumatic Orthopaedics, Peking University People's Hospital, No.11 South Avenue, Xi Zhi Men, Xicheng District, Beijing, 100044, China. drxuefeng@163.com.ORCID http://orcid.org/0000-0002-2968-0084
Dian-Ying ZhangDepartment of Traumatic Orthopaedics, Peking University People's Hospital, No.11 South Avenue, Xi Zhi Men, Xicheng District, Beijing, 100044, China.
Bao-Guo JiangDepartment of Traumatic Orthopaedics, Peking University People's Hospital, No.11 South Avenue, Xi Zhi Men, Xicheng District, Beijing, 100044, China.
Peking University · CN

Funding

Beijing Science and Technology Planning Project D161100002816001Ministry of Education Key Laboratory of trauma treatment and nerve regeneration BMU2019XY007-01
6 · The paper itself

Abstract

backgroundVertebral augmentation is the first-line treatment for the osteoporosis vertebral compression fractures. Bone cement leakage is the most common complication of this surgery. This study aims to assess the risk factors for different types of cement leakage and provides a nomogram for predicting the cement intradiscal leakage.

methodsWe retrospectively reviewed 268 patients who underwent vertebral augmentation procedure between January 2015 and March 2019. The cement leakage risk factors were evaluated by univariate analysis. Different types of cement leakage risk factors were identified by the stepwise logistic analysis. We provided a nomogram for predicting the cement intradiscal leakage and used the concordance index to assess the prediction ability.

resultsA total of 295 levels of vertebrae were included, with a leakage rate of 32.5%. Univariate analysis showed delayed surgery and lower vertebral compression ratio were the independent risk factors of cement leakage. The stepwise logistic analysis revealed percutaneous vertebroplasty was a risk factor in vein cement leakage; delayed surgery, preoperative compression ratio, and upper endplate disruption were in intradiscal cement leakage; age, preoperative fracture severity, and intravertebral vacuum cleft were in perivertebral soft tissue cement leakage; no factor was in spinal canal cement leakage. The nomogram for intradiscal cement leakage had a precise prediction ability with an original concordance index of 0.75.

conclusionsDelayed surgery and more vertebral compression increase the risk of cement leakage. Different types of cement leakage have different risk factors. We provided a nomogram for precise predicting the intradiscal cement leakage.

Indexed as

Fractures, CompressionOsteoporotic FracturesSpinal FracturesVertebroplastyBone CementsHumansNomogramsRetrospective StudiesRisk FactorsSpineBone CementsCement leakageNomogramRisk factorsVertebral augmentationVertebral compression fracture

Identifiers

PMID33256689
PMCPMC7702672
OpenAlexW3108143085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.